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MetabolomicsDissection of two routes to naïve pluripotency using different kinase inhibitors
Embryonic stem cells (ESCs) can be maintained in the naïve state through inhibition of Mek1/2 and Gsk3 (2i). A relevant effect of 2i is the inhibition of Cdk8/19, which are negative regulators of the Mediator complex, responsible for the activity of enhancers. Inhibition of Cdk8/19 (Cdk8/19i) stimul...
2021-02-10 | MTBLS301 | MetaboLights
Unknown"Obesity, metabolic abnormalities and low-grade inflammation: differencial associations with subclinical atherosclerosis".
Not available
S-EPMC12477694 | biostudies-literature
UnknownHepatic SPARC Expression Is Associated with Inflammasome Activation during the Progression of Non-Alcoholic Fatty Liver Disease in Both Mice and Morbidly Obese Patients.
Not available
S-EPMC10573696 | biostudies-literature
Unknownα₂-Adrenoceptor functionality in postmortem frontal cortex of depressed suicide victims.
Not available
S-EPMC3562997 | biostudies-literature
TranscriptomicsmiRNA expression in fast and slow skeletal muscle of wild type and SOD1-G93A mice
Amyotrophic lateral sclerosis (ALS) is a lethal motor neuron disease that progressively debilitates neuronal cells that control voluntary muscle activity. In a mouse model of ALS that expresses mutated human superoxide dismutase 1 (SOD1-G93A) skeletal muscle is one of the tissues affected early by m...
ORGANISM(S): Mus musculus 
2014-03-04 | E-GEOD-55507 | biostudies-arrayexpress
ProteomicsProteomics reveals differential diagnosis biomarkers between sepsis and hemophagocytic syndrome
Hemophagocytic Lymphohistiocytosis (HLH) shares many clinical features with sepsis. To improve HLH diagnosis and its differential diagnosis with sepsis, serum proteomic analyses of healthy donors, HLH and septic patients were performed. In this study, 24 individuals were enrolled in a label free MS/...
ORGANISM(S): Homo sapiens (Human) 
2026-01-05 | PXD063444 | Pride
Hemophagocytic syndrome Sepsis Label free 
TranscriptomicsHereditary Breast Cancer Tumors
Genomic profile of 47 tumors from hereditary breast cancer cases by Array CGH, 7 of which were BRCA mutation carriers (4 in BRCA2 and 3 in BRCA1), previously analyzed for BRCA1 expression by immunohistochemistry. Our goal was to identify specific alterations for BRCA1 not expressing tumors DNA from...
ORGANISM(S): Homo sapiens 
2015-07-07 | E-GEOD-70541 | biostudies-arrayexpress
UnknownRelations between structural and EEG-based graph metrics in healthy controls and schizophrenia patients.
Not available
S-EPMC6866568 | biostudies-literature
UnknownEarly detection of anaemia in primary care with haemoglobinometry: ANHEMOG clinical trial protocol.
Not available
S-EPMC8499500 | biostudies-literature
UnknownAortic flow patterns and wall shear stress maps by 4D-flow cardiovascular magnetic resonance in the assessment of aortic dilatation in bicuspid aortic valve disease.
Not available
S-EPMC5918697 | biostudies-literature
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