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UnknownRole of cetuximab in first-line treatment of metastatic colorectal cancer.
The treatment of metastatic colorectal cancer (mCRC) has evolved considerably in the last decade, currently allowing most mCRC patients to live more than two years. Monoclonal antibodies targeting the epidermal growth factor receptor (EGFR) and vascular endothelial growth factor play an important ro...
S-EPMC3989957 | biostudies-literature
UnknownCluster randomized trial in smoking cessation with intensive advice in diabetic patients in primary care. ITADI Study.

Background

It is a priority to achieve smoking cessation in diabetic smokers, given that this is a group of patients with elevated cardiovascular risk. Furthermore, tobacco has a multiplying effect on micro and macro vascular complications. Smoking abstinence rates increase as the intensity ...
S-EPMC2825223 | biostudies-literature
UnknownClinical features, ventilatory management, and outcome of ARDS caused by COVID-19 are similar to other causes of ARDS.

Purpose

The main characteristics of mechanically ventilated ARDS patients affected with COVID-19, and the adherence to lung-protective ventilation strategies are not well known. We describe characteristics and outcomes of confirmed ARDS in COVID-19 patients managed with invasive mechanical v...
S-EPMC7387884 | biostudies-literature
UnknownAnemia Acuity Effect on Transfusion Strategies in Acute Myocardial Infarction: A Secondary Analysis of the MINT Trial.

Importance

In patients with acute myocardial infarction (MI), limited physiologic adaptation to acute anemia might lead to greater benefit from a liberal red blood cell (RBC) transfusion strategy. Data on such a possible benefit are lacking.

Objectives

To compare acute anemia with chr...
S-EPMC11530937 | biostudies-literature
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