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Background: Adipose tissue-derived stromal cells (ATSCs) hold great promises in regenerative medicine, due to their easy retrieval, high proliferative capacity, and multi-lineage differentiation potential. In the last decade, several studies have reported the plasticity of ATSCs toward a hepatic fat...
ORGANISM(S): Homo sapiens 
Background: Glioblastoma multiforme (GBM) is the most aggressive and most lethal primary malignant brain tumor, correlated with survival rates of less than one year from the time of diagnosis. Current surgical procedure attempts to remove the bulk of the tumor mass, whereas GBM frequently recurs wit...
ORGANISM(S): Homo sapiens 
BACKGROUND: Several in vitro assays have been used to identify “cancer stem cells” (CSC), including expression of cell surface markers and Hoechst dye efflux properties. However, each of these methods has potential pitfalls that complicate interpretation of the results. Focusing on colon cancers (CC...
ORGANISM(S): Homo sapiens 
Metaproteomics investigation of the Gut Microbiota in young subjects with Autism Spectrum Disorders and their relatives
ORGANISM(S): Bacteria (ncbitaxon:2) 
2020-04-06 | MSV000085232 | MassIVE
Objective: identify novel and relevant aspects of Sorafenib action on liver cancer cells. We found that in rat hepatocholangiocarcinoma (LCSC-2) cells, exposure to the MEK/multikinase inhibitor sorafenib did not inhibit ERK phosphorylation nor induced appreciable cell death in the low micromolar ra...
ORGANISM(S): Rattus norvegicus 
Metaproteomic study on fecal samples collected from Crohn's Disease (CD) patients and some Household Healthy Controls (HHC) during an eight week Lof Fat/High fiber diet intervention. Stoo sampling was performed at baseline (V1), week 8 (V2) and week 36 (V3). Protein Identification and quantitation ...
ORGANISM(S): Bacteria Homo Sapiens (ncbitaxon:9606) 
2024-02-01 | MSV000093975 | MassIVE
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