The study of protein-protein interactions is increasingly relying on mass spectrometry (MS). The classical approach of separating immunoprecipitated proteins by SDS-PAGE followed by in-gel digestion is long and labour-intensive. Besides, it is difficult to integrate it with most quantitative MS-base...
LC-MSMS analyses of extract coltures of Microbispora corallina producing the lantibiotic NAI-107 (aka microbisporicin) and Nonomuraea sp. ATCC39727 producing the glycopeptide A40926