The susceptibility to chronic social isolation (CSIS) is associated with development of major depression (MD). Recent studies relate MD with altered expression of synaptic proteins in specific brain regions, whereby some individuals exposed to the stressors are resistant to the stress. To explore th...
We investigated the relative quantification of proteins in hippocampal cytosolic and nonsynaptic mitochondrial (NSM) fractions of rats exposed to chronic social isolation (CSIS), an animal model of depression, comparing CSIS-resilient with CSIS-sensitive or control rats, via a comparative subproteom...
We report cell-type specific ribosome profiling in a mouse glioma model. We report a strategy for cell-type specific ribosome profiling in vivo. Our strategy was applied to the characterization of a mouse glioma model.
Dysregulation of brain synaptic proteins caused by chronic psychosocial stress has been linked with the development of major depression (MD). To gain insights into the pattern of synaptic proteome changes and different biological functions and pathways underlying MD and drug action, a comparative pr...
