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TranscriptomicsWhole genome transcription profiling of the JN-DSCRT1 cell line treated with Trabectedin
The purpose of experiments consisted in studying the mode of action of Trabectedin in Desmoplastic Small Round Cell Tumor (DSRCT). In order to investigate the effects of Trabectedin in the expression of EWS-WT1 target genes in relation to the drug growth inhibitory effect, the JN-DSCRT-1 cell line w...
ORGANISM(S): Homo sapiens 
2017-01-27 | E-MTAB-4532 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of patient-derived xenograft models of myxoid liposarcoma either responsive or resistant to trabectedin treatment.
Transcriptional profiling of patient-derived xenograft models of myxoid liposarcoma with either FUS-CHOP type I, named as ML017, or FUS-CHOP type III, named as ML006. Both ML017 and ML006 are responsive to trabectedin treatment, while model ML017/ET has aquired resistance to the drug. Samples are ei...
ORGANISM(S): Homo sapiens 
2020-01-10 | E-MTAB-8632 | biostudies-arrayexpress
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