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TranscriptomicsGene expression study in CLL of B-cell receptor triggering (mRNA Study)
The B-cell receptor (BCR) plays an important role in pathogenesis and progression of chronic lymphocytic leukemia (CLL). We investigated the BCR triggering-dependent mRNA modulation by stimulating CLL cells with immobilized anti-IgM. miRome of immobilized anti-IgM stimulated CLL cells (n=16) identif...
ORGANISM(S): Homo sapiens 
2014-01-01 | E-GEOD-52774 | biostudies-arrayexpress
TranscriptomicsGene expression study in CLL of B-cell receptor triggering (miRNA study)
The B-cell receptor (BCR) plays an important role in pathogenesis and progression of chronic lymphocytic leukemia (CLL). We investigated the BCR triggering-dependent microRNA modulation by stimulating CLL cells with immobilized anti-IgM. miRome of immobilized anti-IgM stimulated CLL cells (n=16) ide...
ORGANISM(S): Homo sapiens 
2014-01-01 | E-GEOD-52775 | biostudies-arrayexpress
TranscriptomicsmiRNA expression profile of unmutated and mutated CLL cells
The aim is to identify the differential miRNA expression profile of B-CLL stimulated with different type of stimulation CPG One color design, 36 samples, Two-condition experiment, CPG-stimulated B-CLL unmutated and mutated vs. Unstimulated B-CLL unmutated and mutated. Biological replicates: 18 uns...
ORGANISM(S): Homo sapiens 
2011-06-30 | E-GEOD-30106 | biostudies-arrayexpress
TranscriptomicsmiRNA and mRNA expression profile of CLL cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2011-06-30 | E-GEOD-30107 | biostudies-arrayexpress
TranscriptomicsCPG stimulation for Gene Expression of unmutated B-CLL
The aim is to identify the differential gene expression profile of unmutated B-CLL stimulated with CPG. Two-condition experiment, CPG-stimulated B-CLL unmutated vs. Unstimulated B-CLL unmutated . Biological replicates: 9 unstimulated replicates, 9 CPG-stimulated replicates. Reference design;
ORGANISM(S): Homo sapiens 
2011-06-30 | E-GEOD-30105 | biostudies-arrayexpress
GenomicsHigh density copy number analysis and whole exome sequencing of chronic lymphocytic leukemia

The pathogenesis of chronic lymphocytic leukemia (CLL), the most common leukemia in adults, is still largely unknown since the full spectrum of genetic lesions that are present in the CLL genome, and therefore the number and identity of dysregulated cellular pathways, have not been iden...

phs000364.v1.p1 | EGA
TranscriptomicsCPG stimulation for Gene Expression of mutated B-CLL
The aim is to identify the differential gene expression profile of mutated B-CLL stimulated with CPG Two-condition experiment, CPG-stimulated B-CLL mutated vs. Unstimulated B-CLL mutated . Biological replicates: 8 unstimulated replicates, 8 CPG-stimulated replicates. Reference design;
ORGANISM(S): Homo sapiens 
2011-08-17 | E-GEOD-31360 | biostudies-arrayexpress
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