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MetabolomicsSequential multi-omics analysis identifies clinical phenotypes and predictive biomarkers for long COVID

The post-acute sequelae of COVID-19 (PASC), also known as long COVID, is often associated with debilitating symptoms and adverse multisystem consequences. We obtain plasma samples from 117 individuals during and 6 mth following their acute phase of infection to comprehensively profile and as...

2024-02-23 | MTBLS7337 | MetaboLights
GenomicsType 1 Diabetes Genetics Consortium (T1DGC): Genome-Wide Association Study in Type 1 Diabetes, 2008

Cases with Type 1 Diabetes (T1D) in the UK, were part of the Wellcome Trust Case Control Consortium (WTCCC) - http://www.wtccc.org.uk - that first reported in 2007:

Wellcome Trust Case Control Consortium (2007) Genome-wide association s...

phs000180.v2.p2 | EGA
TranscriptomicsTranscription profiling of fission yeast treated with hydrogen peroxide in fission yeast wild type and csx1 mutant cells
Time course experiments of hydrogen peroxide treated cells for both S. pombe wild type and csx1 mutant cells.
ORGANISM(S): Schizosaccharomyces pombe 
2004-10-01 | E-MEXP-176 | biostudies-arrayexpress
GenomicsLive cell monitoring of periodic gene expression in synchronous human cells identifies forkhead genes involved in cell cycle control
We report the genome wide DNA binding patterns of wild type FOXK1 in asynchronous HeLa cells using chromatin precipitation followed by high-throughput sequencing (ChIP-seq). We find that FOXK1 is bound to the promoter of a number of cell cycle genes including the E2F binding partner TFDP1. This st...
ORGANISM(S): Homo sapiens 
2012-07-09 | E-GEOD-39138 | biostudies-arrayexpress
TranscriptomicsDistribution of different proteins related to sister chromatid cohesion during the cell cycle.
This series is a supplementary data set for the manuscript titled "Cohesin relocation from sites of chromosomal loading to places of convergent transcription" All data shown in the paper were registered (30 ChIP-chip and one transcription data). Experimental design: 1. Type of experiment: a. ChIP ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-06-09 | E-GEOD-1461 | biostudies-arrayexpress
GenomicsPNG_GWAS-2.5M_b37_2019
EGAS00001001311: Genome-wide study of resistance to severe malaria in eleven worldwide populations:PNG
EGAD00010001735 | EGA
GenomicsIdentification of cell cycle-regulated genes periodically expressed in U2OS cells and their regulation by FOXM1 and E2F transcription factors [ChIP-seq]
We report the genome wide DNA binding patterns of wild type FOXM1 in asynchronous HeLa cells using chromatin precipitation followed by high-throughput sequencing (ChIP-seq). We find that FOXM1 is bound to the promoter of a number of cell cycle genes including PLK, AURKB, and CCNB1. FOXM1 ChIP-seq i...
ORGANISM(S): Homo sapiens 
2013-11-06 | E-GEOD-52098 | biostudies-arrayexpress
TranscriptomicsIdentification of cell cycle-regulated genes periodically expressed in U2OS cells and their regulation by FOXM1 and E2F transcription factors
We identified the cell cycle-regulated mRNA transcripts genome-wide in the osteosarcoma derived U2OS cell line. This resulted in 2,140 transcripts mapping to 1,871 unique cell cycle-regulated genes that show periodic oscillations across multiple synchronous cell cycles. We identified genomic loci ...
ORGANISM(S): Homo sapiens 
2013-10-11 | E-GEOD-50988 | biostudies-arrayexpress
GenomicsIdentification of cell cycle-regulated genes periodically expressed in U2OS cells and their regulation by FOXM1 and E2F transcription factors
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-11-06 | E-GEOD-52100 | biostudies-arrayexpress
TranscriptomicsER alpha rapid signaling is required for estrogen induced proliferation and migration of vascular endothelial cells
Estrogen receptor alpha (ERa) is required for the protective effects of 17-beta-estradiol (E2, the active, endogenous form of estrogen) after vascular injury or in atherosclerosis. E2-bound ERa can function as a transcription factor which binds directly to chromatin (the genomic pathway). Some ERa i...
ORGANISM(S): Homo sapiens 
2016-03-22 | E-GEOD-72180 | biostudies-arrayexpress
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