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TranscriptomicsPTIP-regulated genes in MEF
PPARg and C/EBPa cooperate to control preadipocyte differentiation (adipogenesis). However, the factors that regulate PPARg and C/EBPa expression during adipogenesis remain largely unclear. Here we show PTIP, a protein that associates with histone H3K4 methyltransferases, regulates PPARg and C/EBPa ...
ORGANISM(S): Mus musculus 
2009-05-29 | E-GEOD-16263 | biostudies-arrayexpress
TranscriptomicsSphingosine-1-phosphate Phosphatase 2 Regulates Pancreatic Islet B-cell Endoplasmic Reticulum Stress and Proliferation
Sphingosine-1-phosphate (S1P) is a sphingolipid metabolite that regulates basic cell functions through metabolic and signaling pathways. Intracellular metabolism of S1P is controlled, in part, by two homologous S1P phosphatases, 1 and 2, which are encoded by Sgpp1 and Sgpp2, respectively. S1P phosph...
ORGANISM(S): Mus musculus 
2016-07-25 | E-GEOD-73131 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of adult C57BL6 mouse tissues and 3T3-L1 fibroblasts
This SuperSeries is composed of the following subset Series:; GSE6793: Expression data from select tissues harvested from C57BL6 mice; GSE6794: Expression data from 3T3-L1 adipogenesis Experiment Overall Design: Refer to individual Series

Note: GSM156880.CEL is not available from GEO.
ORGANISM(S): Mus musculus 
2007-11-06 | E-GEOD-6795 | biostudies-arrayexpress
TranscriptomicsProtection from obesity and diabetes by blockade of TGF-beta/Smad3 signaling
Imbalances in glucose and energy homeostasis are at the core of the worldwide epidemic of obesity and diabetes. Here, we illustrate an important role of the TGF-beta/Smad3 signaling pathway in regulating glucose and energy homeostasis. Smad3 deficient mice are protected from diet-induced obesity and...
ORGANISM(S): Mus musculus 
2011-07-12 | E-GEOD-28598 | biostudies-arrayexpress
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