Sort   by:  
 Page size 
ProteomicsProteome analysis of GCN1 CKO mouse liver
Tamoxifen-inducible conditional knockout (CKO) mice were generated to explore the function of Gcn1 in adult mice using the Cre/loxP system. To analyze the function of GCN1 in the liver, we compared the whole cell proteome of livers harvested from GCN1 CKO mice with that of wild-type mice.
ORGANISM(S): Mus Musculus (mouse) 
2023-04-01 | PXD030514 | JPOST Repository
ProteomicsProteome analysis of GCN1 CKO mouse jejunum
Tamoxifen-inducible conditional knockout (CKO) mice were generated to explore the function of Gcn1 in adult mice using the Cre/loxP system. To analyze the function of GCN1 in the intestinal epithelium, we compared the whole cell proteome of jejunum harvested from GCN1 CKO mice with that of wild-type...
ORGANISM(S): Mus Musculus (mouse) 
2022-08-29 | PXD030519 | JPOST Repository
ProteomicsProteome analysis of GCN1 CKO mouse ileum
Tamoxifen-inducible conditional knockout (CKO) mice were generated to explore the function of Gcn1 in adult mice using the Cre/loxP system. To analyze the function of GCN1 in the intestinal epithelium, we compared the whole cell proteome of ileum harvested from GCN1 CKO mice with that of wild-type m...
ORGANISM(S): Mus Musculus (mouse) 
2024-03-31 | PXD030518 | JPOST Repository
ProteomicsProteome analysis of GCN1 CKO mouse duodenum
Tamoxifen-inducible conditional knockout (CKO) mice were generated to explore the function of Gcn1 in adult mice using the Cre/loxP system. To analyze the function of GCN1 in the intestinal epithelium, we compared the whole cell proteome of duodenum harvested from GCN1 CKO mice with that of wild-typ...
ORGANISM(S): Mus Musculus (mouse) 
2024-03-31 | PXD030517 | JPOST Repository
ProteomicsProteome analysis of GCN1 CKO mouse inguinal white adipose tissue (iWAT)
Tamoxifen-inducible conditional knockout (CKO) mice were generated to explore the function of Gcn1 in adult mice using the Cre/loxP system. To analyze the function of GCN1 in the inguinal white adipose tissue (iWAT), we compared the whole cell proteome of eWAT harvested from GCN1 CKO mice with that ...
ORGANISM(S): Mus Musculus (mouse) 
2024-03-31 | PXD030516 | JPOST Repository
GenomicsMechanisms of stop codon readthrough mitigation reveal principles of GCN1 mediated translational quality control
Mechanisms of stop codon readthrough mitigation reveal principles of GCN1 mediated translational quality control
PRJNA885130 | ENA
GenomicsEffects of Triad1-knockdown on ribosome/polysome profiles are reversed by Gcn1-knockdown
Effects of Triad1-knockdown on ribosome/polysome profiles are reversed by Gcn1-knockdown
PRJNA1196904 | ENA
TranscriptomicsMechanisms of stop codon readthrough mitigation reveal principles of GCN1 mediated translational quality control
Readthrough into the 3′ untranslated region (3′UTR) of the mRNA results in the production of aberrant proteins. Metazoans efficiently clear readthrough proteins, but the underlying mechanisms remain unknown. Here, we show in C. elegans and mammalian cells that readthrough proteins are targeted by a ...
ORGANISM(S): Caenorhabditis elegans Homo sapiens 
2023-05-15 | GSE214396 | GEO
UnknownStructure of Gcn1 bound to stalled and colliding 80S ribosomes.
Not available
S-EPMC8040806 | biostudies-literature
UnknownA genetic approach to identify amino acids in Gcn1 required for Gcn2 activation.
Not available
S-EPMC9704636 | biostudies-literature
Sort   by:  
 Page size