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UnknownA GCSFR/CSF3R zebrafish mutant models the persistent basal neutrophil deficiency of severe congenital neutropenia.
Not available
S-EPMC5345067 | biostudies-literature
UnknownAlternatively spliced, truncated GCSF receptor promotes leukemogenic properties and sensitivity to JAK inhibition.
Not available
S-EPMC5875430 | biostudies-literature
TranscriptomicsTranscription profiling of human CD16+ and CD16- peripheral blood monocytes from healthy individuals
Human peripheral blood monocytes (Mo) consist of subsets distinguished by expression of CD16 (FCGRIII) and chemokine receptors. Classical CD16- Mo express CCR2 and migrate in response to CCL2, while a minor CD16+ Mo subset expresses CX3CR1 and migrates into tissues expressing CX3CL1. CD16+ Mo produc...
ORGANISM(S): Homo sapiens 
2009-09-15 | E-GEOD-16836 | biostudies-arrayexpress
UnknownGranulopoiesis requires increased C/EBPα compared to monopoiesis, correlated with elevated Cebpa in immature G-CSF receptor versus M-CSF receptor expressing cells.
Not available
S-EPMC3994156 | biostudies-literature
UnknownPotential diagnostic and drug target markers in glioblastoma.
Not available
S-EPMC10973500 | biostudies-literature
UnknownMPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia.
Not available
S-EPMC1502153 | biostudies-literature
UnknownEvolutionarily conserved mechanisms regulating stress-induced neutrophil redistribution in fish.
Not available
S-EPMC10954836 | biostudies-literature
TranscriptomicsRNA sequencing comparing the effect of the introduction of CSF3R-d715 in control- or SCN- hematopoietic progenitor cells (HPCs)
To address how CSF3R mutations affect hematopoiesis in a severe congenital neutropenia (SCN) background we used SCN patient, or control, derived induced pluripotent stem cells (iPSC). HPCs were generated from CRISPR-Cas9 genome edited CSF3R-d715 SCN or control-derived iPSCs with the STEMdiff™ Hemato...
ORGANISM(S): Homo sapiens 
2021-04-01 | E-MTAB-10288 | biostudies-arrayexpress
UnknownActivating JAK2 mutants reveal cytokine receptor coupling differences that impact outcomes in myeloproliferative neoplasm.
Not available
S-EPMC5589508 | biostudies-literature
UnknownCharacterization of myeloperoxidase and its contribution to antimicrobial effect on extracellular traps in flounder (Paralichthys olivaceus).
Not available
S-EPMC9908613 | biostudies-literature
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