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TranscriptomicsGene expression after focal demyelination of the corpus callosum
To determine expression profiles of cytokines and growth factor profiles in the subventricular zone (SVZ) after demyelination we performed gene array analysis. In SVZ after 4 days post lesin (dpl) LPC-injected tissue, demonstrated regulation of BMP pathway elements, including increased chordin, nogg...
ORGANISM(S): Mus musculus 
2010-04-13 | E-GEOD-21310 | biostudies-arrayexpress
ProteomicsPyruvate kinase M2 modification by a lipid peroxidation byproduct acrolein contributes to kidney fibrosis
This study used a proteomic approach with an anti-Acr-PC antibody followed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis to identify several acrolein-modified protein targets. Among these protein targets, pyruvate kinase M2 (PKM2) was found to be modified by acrolein at Cys35...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD040335 | Pride
Renal fibrosis  acrolein  pyruvate kinase m2  hypoxia-inducible factor 1-alpha  hydralazine  carnosine. 
TranscriptomicsIdentification of WRKY22 direct targets under submergence in Arabidopsis with ChIP
To identify direct targets of WRKY22, we created a transgenic Arabidopsis line that expresses a c-myc epitope-tagged WRKY22 and used ChIP followed by microarray hybridization (ChIP-chip) to screen for candidates and validate the in vivo protein-DNA interactions with ChIP followed by quantitative PCR...
ORGANISM(S): Arabidopsis thaliana 
2013-07-03 | E-GEOD-40138 | biostudies-arrayexpress
UnknownThe Role of Family Health in Mediating the Association between Smartphone Use and Health Risk Behaviors among Chinese Adolescent Students: A National Cross-Sectional Study
Not available
S-EPMC9603663 | biostudies-literature
ProteomicsWheat leaf phosphoproteome under drought stress
Waxy starch has an important influence on the qualities of breads. Generally, grain weight and yield in waxy wheat (Triticum aestivum L.) are significantly lower than in bread wheat. In this study, we performed the first proteomic and phosphoproteomic analyses of starch granule-binding proteins by c...
ORGANISM(S): Triticum aestivum (Wheat) 
2017-01-17 | PXD000646 | Pride
Bread wheat  drought stress  phosphoproteome  phosphorylation status 
UnknownAntioxidant Defenses in the Brains of Bats during Hibernation.
Not available
S-EPMC4806925 | biostudies-literature
UnknownImmune Responses to a Recombinant Glycoprotein E Herpes Zoster Vaccine in Adults Aged 50 Years or Older.
Not available
S-EPMC5946839 | biostudies-literature
TranscriptomicsThe gene expression changes in darkcd4 apoptosis-deficient mutant flies
Apoptosis is required not only for proper morphogenesis and tissue size regulation during development, but also for removing damaged or unwanted cells to maintain homeostasis. Apoptosis is mainly executed by evolutionally-conserved signaling process including caspases and its activator, dark. We per...
ORGANISM(S): Drosophila melanogaster 
2014-06-26 | E-GEOD-47853 | biostudies-arrayexpress
TranscriptomicsSmall RNA deep-sequencing identifies microRNAs and other small non-coding RNAs from human herpesvirus 6 (HHV-6B)
Roseolovirus, or human herpesvirus 6 (HHV-6) is a ubiquitous human pathogen infecting over 95% of the population by the age of two years. As with other herpesviruses, reactivation of HHV-6 can present with severe complications in immunocompromised individuals. Recent studies have highlighted the imp...
ORGANISM(S): Human herpesvirus 6B 
2012-01-01 | E-GEOD-34196 | biostudies-arrayexpress
UnknownIGESS: a statistical approach to integrating individual-level genotype data and summary statistics in genome-wide association studies.
Not available
S-EPMC5860575 | biostudies-literature
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