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MetabolomicsDynamic partitioning of branched-chain amino acids-derived nitrogen supports renal cancer progression

Metabolic reprogramming is critical for tumor initiation and progression. However, the exact impact of specific metabolic changes on cancer progression is poorly understood. Here, we integrate multimodal analyses of primary and metastatic clonally-related clear cell renal cancer cells (ccRCC) gro...

2022-12-08 | MTBLS5615 | MetaboLights
MetabolomicsResource Partitioning of Diatom Metabolites that Support Bacterial Heterotrophy in the Ocean (NMR assay)

The communities of marine bacteria that assemble around living microphytoplankton are predictably dominated by three taxonomic groups, each of which specializes in the use or transport of different components of the available metabolite pool: Rhodobacterales transport small and polar metabolites,...

2020-09-15 | MTBLS1544 | MetaboLights
MetabolomicsMetabolic cooperation and spatiotemporal niche partitioning in a kefir microbial community; Kefir fermentation curve (FIA-MS)

Microbial communities often undergo intricate compositional changes yet also maintain stable coexistence of diverse species. The mechanisms underlying long-term coexistence remain unclear, as system-wide studies have been largely limited to engineered communities, ex situ adapted cultures, or syn...

2020-11-04 | MTBLS1829 | MetaboLights
MetabolomicsResource Partitioning of Diatom Metabolites that Support Bacterial Heterotrophy in the Ocean (UPLC-MS assay)

The communities of marine bacteria that assemble around living microphytoplankton are predictably dominated by three taxonomic groups, each of which specializes in different components of the available metabolite pool: Rhodobacterales transport small and polar metabolites, Flavobacteriia use carb...

2020-09-15 | MTBLS1751 | MetaboLights
MetabolomicsMetabolic cooperation and spatiotemporal niche partitioning in a kefir microbial community; Interaction between the kefir isolates Lactococcus lactis and Acetobacter fabarum (GC-MS)

Microbial communities often undergo intricate compositional changes yet also maintain stable coexistence of diverse species. The mechanisms underlying long-term coexistence remain unclear, as system-wide studies have been largely limited to engineered communities, ex situ adapted cultures, or syn...

2020-11-04 | MTBLS1830 | MetaboLights
ProteomicsAdaptive partitioning of a gene locus to the nuclear envelope in Saccharomyces cerevisiae is driven by polymer-polymer phase separation
Partitioning of active gene loci to the nuclear envelope is a key mechanism by which organisms can increase the speed of adaptation and metabolic robustness to fluctuating resources in the environment. In the budding yeast Saccharomyces cerevisiae, adaptation and transcriptional memory induced by nu...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-03-01 | PXD029913 | Pride
Active gene Nuclear envelope Ino1 Gene partitioning Chromatin decompaction Active chromatin Phase separation 
MetabolomicsMetabolic cooperation and spatiotemporal niche partitioning in a kefir microbial community; Interaction between the kefir isolates Lactococcus lactis and Acetobacter (spent-medium assay, measured untargeted (FIA-qTOF) and targeted (HILIC, LC-MS)

Microbial communities often undergo intricate compositional changes yet also maintain stable coexistence of diverse species. The mechanisms underlying long-term coexistence remain unclear, as system-wide studies have been largely limited to engineered communities, ex situ adapted cultures, or syn...

2020-11-04 | MTBLS1823 | MetaboLights
TranscriptomicsTranscriptome partitioning for mRNA translation in hypoxia
Protein synthesis belongs to the most energy consuming processes in the cell. Lowering oxygen tension below normal (hypoxia) causes a rapid inhibition of global mRNA translation due to the decreased availability of energy. Interestingly, subsets of mRNAs pursue active translation under such circumst...
ORGANISM(S): Homo sapiens 
2015-04-01 | E-GEOD-49029 | biostudies-arrayexpress
GenomicsFunctional partitioning of transcriptional regulators by patterned charge blocks
Functional partitioning of transcriptional regulators by patterned charge blocks
PRJNA867741 | ENA
GenomicsCpG island mediated linear and spatial gene partitioning (RNA-seq)
CpG island mediated linear and spatial gene partitioning (RNA-seq)
PRJNA319992 | ENA
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