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MetabolomicsMelatonin enhances function of porcine immature Sertoli cells via modulating gene expression and metabolism

Melatonin (MT), a neurohormone synthesized and secreted primarily by the pineal gland, is of vital function to animal reproduction. However, the effect of MT treatment on porcine immature Sertoli cells (iSCs) remains unclear. Here, MT treatment (10 nM, 36 h) could elevate mitochondrial function a...

2025-01-06 | MTBLS11126 | MetaboLights
TranscriptomicsCMV-Specific CD8+ Memory T Cells Re-Emerge After Viral Challenge And Recapitulate CMV Immunity Under Various Adoptive Transfer Conditions
Reconstitution of cytomegalovirus (CMV)-specific immunity following transplant remains a primary clinical objective to prevent CMV disease, and adoptive immunotherapy of CMV-specific T cells can be an effective therapeutic approach. Due to the persistence of CMV, most CMV-specific CD8+ T cells becom...
ORGANISM(S): Mus musculus 
2015-01-28 | E-GEOD-61927 | biostudies-arrayexpress
TranscriptomicsCoxiella burnetii, the agent of Q fever, persists in adipocytes
Coxiella burnetii, the agent of Q fever, persists in humans despite specific immune responses: however, its reservoir remains unknown. We detected C. burnetii in adipose tissue from BALB/c and C57/BL6 mice 4 months after infection when no bacteria were found in other tissues. C. burnetii infected cu...
ORGANISM(S): Mus musculus 
2014-05-25 | E-GEOD-46335 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse skeletal muscle after gene transfer by electroporation vs. Controls
Abstract; Background: Gene transfer by electroporation (electro gene transfer) to muscle results in high level long term transgenic expression, showing great promise for treatment of e.g. protein deficiency syndromes. However little is known about the effects of electro gene transfer on muscle fibre...
ORGANISM(S): Mus musculus 
2009-04-23 | E-GEOD-6686 | biostudies-arrayexpress
GenomicsControl of a gene transfer agent cluster in Caulobacter crescentus by transcriptional activation and anti-termination
Control of a gene transfer agent cluster in Caulobacter crescentus by transcriptional activation and anti-termination
PRJNA1036642 | ENA
ProteomicsProtein ID of ϕXacN1
ϕXacN1 is a novel jumbo myovirus infecting the causative agent of Asian citrus canker, Xanthomonas citri. Its linear 384,670 bp double-stranded DNA genome encodes 592 predicted protein coding genes and shows 65,875 bp direct terminal repeats (DTRs), so far the longest DTRs among sequence phage genom...
ORGANISM(S): Cellular Organisms 
2018-10-30 | PXD008065 | JPOST Repository
UnknownOccurrence and expression of gene transfer agent genes in marine bacterioplankton.
Not available
S-EPMC2394915 | biostudies-literature
TranscriptomicsDNA packaging bias and differential expression of gene transfer agent genes within a population during production and release of the Rhodobacter capsulatus gene transfer agent, RcGTA
Rhodobacter capsulatus produces a gene transfer agent (GTA) called RcGTA. RcGTA is a phage-like particle that packages R. capsulatus DNA and transfers it to other R. capsulatus cells. Low-resolution techniques suggested RcGTA packages random DNA. Analysis of the RcGTA terminase sequence revealed a d...
ORGANISM(S): Rhodobacter capsulatus 
2012-05-22 | GSE33176 | GEO
TranscriptomicsDNA packaging bias and differential expression of gene transfer agent genes within a population during production and release of the Rhodobacter capsulatus gene transfer agent, RcGTA
Rhodobacter capsulatus produces a gene transfer agent (GTA) called RcGTA. RcGTA is a phage-like particle that packages R. capsulatus DNA and transfers it to other R. capsulatus cells. Low-resolution techniques suggested RcGTA packages random DNA. Analysis of the RcGTA terminase sequence revealed a d...
ORGANISM(S): Rhodobacter capsulatus 
2012-05-21 | E-GEOD-33176 | biostudies-arrayexpress
TranscriptomicsMaternal cecal microbiota transfer rescues early-life antibiotic-induced enhancement of type 1 diabetes in mice-the long term restoration
Early-life antibiotic exposure perturbs the intestinal microbiota, alters innate intestinal immunity, and accelerates type 1 diabetes development in the NOD mouse model. Here we found that maternal cecal microbiota transfer (CMT) to NOD mice with early-life antibiotic perturbation partially rescued ...
ORGANISM(S): Mus musculus 
2021-09-02 | E-MTAB-9982 | biostudies-arrayexpress
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