Genetic screen - OmicsDI

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Unknown (6967)
Genomics (2064)
Transcriptomics (1914)
Proteomics (215)
Other (193)
Metabolomics (48)
Methylation profiling (24)
Genomic (22)
Clinical (2)
Multiomics (1)

Organisms

Homo sapiens (1072)
Mus musculus (601)
Arabidopsis thaliana (147)
Drosophila melanogaster (104)
Saccharomyces cerevisiae (87)
Caenorhabditis elegans (78)
Danio rerio (64)
Rattus norvegicus (31)
Schizosaccharomyces pombe (30)
synthetic construct (19)
Gallus gallus (16)
Escherichia coli (14)
Glycine max (9)
Triticum aestivum (8)
Oryza sativa (7)
Sus scrofa (6)
Xenopus laevis (5)
Zea mays (5)
Solanum lycopersicum (5)
Agrobacterium tumefaciens (5)
Chlamydomonas reinhardtii (4)
Streptomyces coelicolor A3(2) (4)
Helicobacter pylori (4)
Streptomyces venezuelae (4)
Salmonella enterica subsp. enterica serovar Typhimurium (4)
Lemna minor (3)
Spodoptera frugiperda (3)
Fundulus heteroclitus (3)
Daphnia magna (3)
Apis mellifera (3)

Organisms

Homo sapiens (543)
Mus musculus (295)
Arabidopsis thaliana (74)
Caenorhabditis elegans (47)
Drosophila melanogaster (43)
Saccharomyces cerevisiae (35)
Danio rerio (27)
Schizosaccharomyces pombe (15)
Neurospora crassa (6)
Glycine max (6)
Candida albicans (6)
Escherichia coli (5)
Rattus norvegicus (5)
Aspergillus niger (4)
Gallus gallus (4)
Escherichia coli str. K-12 substr. MG1655 (3)
Chlorocebus sabaeus (3)
Oryza sativa (3)
Bacillus subtilis (3)
Vitis vinifera (3)
Bos taurus (3)
Caulobacter vibrioides CB15 (2)
Salpingoeca rosetta (2)
Saccharomyces cerevisiae S288C (2)
Aspergillus nidulans (2)
Pseudomonas aeruginosa UCBPP-PA14 (2)
Dictyostelium discoideum (2)
Agrobacterium tumefaciens (2)
Hordeum vulgare (2)
Mycosarcoma maydis (2)

Repository

ENA (1712)
biostudies-arrayexpress (1337)
geo (1080)
pride (125)
EGA (74)
MassIVE (49)
MetaboLights (43)
iProX (26)
dbGaP (22)
jPOST (6)
GNPS (5)
PanoramaPublic (2)
PeptideAtlas (2)
EVA (1)
LINCS (1)

Tissue

Cell culture (35)
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Whole body (3)
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Blood serum (2)
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Testis (2)
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Blood (1)
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Disease

Normal (5)
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Unspecified peripheral T-cell lymphoma (1)
T. circumcincta infection (1)
Model of metabolic syndrome (1)
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Whitehart (1)
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NGT (1)
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Chicken Anaemia Virus infected (1)
Glioblastoma (1)
Cerebral ischemia (1)
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Neoplasms (1)
Acute leukemia (1)
Age related macular degeneration (1)

Technology Type

Mass Spectrometry (125)
Shotgun proteomics (67)
Mass spectrometry (28)
Affinity purification coupled with mass spectrometry proteomics (28)
Bottom-up proteomics (24)
Data-dependent acquisition (16)
Mass spectrometry assay (15)
Gel-based experiment (6)
Illumina HiSeq 2000 (5)
Data-independent acquisition (5)
Illumina MiSeq (2)
Illumina HiSeq 2000, ILLUMINA (2)
Affinity proteomics (2)
Chemical cross-linking coupled with mass spectrometry proteomics (2)
Top-down proteomics (2)
Illumina HiSeq 2500, ILLUMINA (1)
ILLUMINA, Illumina HiSeq 2500 (1)
Illumina HiSeq 2000, Illumina MiSeq, ILLUMINA, Illumina HiSeq 2500 (1)
ILLUMINA, Illumina HiSeq 2000 (1)
Illumina HiSeq 2500 (1)
ILLUMINA, Illumina Genome Analyzer II, Illumina HiSeq 2000 (1)
Illumina HiSeq 2000, Illumina_2.5M (1)
Illumina Genome Analyzer II, Illumina HiSeq 2000 (1)
Fluorescence imaging (1)
Fluorescence intensity (1)
All-ion fragmentation (1)
HDMSE (1)
SRM/MRM (1)
SWATH MS (1)

Instrument Platform

Illumina NovaSeq 6000 (47)
Illumina HiSeq 2000 (37)
Illumina HiSeq 4000 (32)
NextSeq 500 (32)
Illumina HiSeq 2500 (19)
Illumina MiSeq (13)
Illumina Genome Analyzer IIx (7)
ScanArray 5000 [PerkinElmer] (5)
418 [Affymetrix] (4)
Axon GenePix 4000B scanning hardware (4)
NextSeq 550 (4)
Illumina Genome Analyzer II (3)
NextSeq 2000 (3)
454 GS FLX+ (2)
G2565BA DNA microarray scanner [Agilent] (2)
Scanning hardware (2)
Illumina NovaSeq X (2)
NA (2)
Illumina HiSeq 1000 (2)
Illumina HiSeq 3000 (2)
Chromium Controller, 10x Genomics and Chromium X, 10x Genomics (1)
Chromium Controller, 10x Genomics and Chromium X, 10x Genomics (1)
Cell culture (1)
Dell PowerEdge R750; CPU: 2 × Intel Xeon Gold 6346 (32 Cores / 64 Threads); RAM: 188 GB (1)
RapidPURE RNA Plant Kit (MP Biomedicals, Illkirch, France) (1)
FastPrep-24 homogeniser (1)
BSL2 Laboratory (1)
MacBook Pro 64Gb RAM; 16-core (1)
Qubit 2.0 Fluorometer; Agilent TapeStation 4200 (1)
Microarray scanner system (1)

Publication Date

2025 (245)
2010 (223)
2026 (206)
2013 (176)
2024 (165)
2011 (143)
2014 (142)
2023 (140)
2022 (138)
2021 (136)
2015 (127)
2012 (127)
2008 (108)
2016 (101)
2020 (100)
2019 (78)
2009 (78)
2018 (57)
2017 (54)
2007 (53)
2005 (27)
2006 (21)
2004 (5)
2003 (4)

UNIPROT ID/AC

A0A024RC46 (1)
A0A087WTX5 (1)
A0A087WUD1 (1)
A0A087WVW2 (1)
A0A087WXI0 (1)
A0A087WYL9 (1)
A0A087X130 (1)
A0A087X1V9 (1)
A0A0A0MR66 (1)
A0A0A0MS07 (1)
A0A0A0MS51 (1)
A0A0B4J220 (1)
A0A0C4DG89 (1)
A0A9S2 (1)
A0FGR8 (1)
A0FGR8-2 (1)
A0FGR8-6 (1)
A0M8Q6 (1)
A1L170 (1)
A1X3T7 (1)
A2NUT2 (1)
A2V8C3 (1)
A3QM97 (1)
A3QMB9 (1)
A3QMC5 (1)
A3QMC8 (1)
A4D110 (1)
A4F255 (1)
A4UVK2 (1)
A4UVL1 (1)

ENSEMBL ID

ENSG00000170477 (1)

CHEBI ID

CHEBI:17509 (5)
CHEBI:30769 (5)
CHEBI:22470 (4)
CHEBI:30805 (4)
CHEBI:34306 (4)
CHEBI:17927 (4)
CHEBI:28875 (4)
CHEBI:30746 (4)
CHEBI:33135 (4)
CHEBI:21891 (4)
CHEBI:27823 (4)
CHEBI:17568 (4)
CHEBI:73024 (4)
CHEBI:16467 (4)
CHEBI:18019 (4)
CHEBI:17203 (4)
CHEBI:35932 (4)
CHEBI:55328 (4)
CHEBI:73722 (4)
CHEBI:132983 (4)
CHEBI:16411 (4)
CHEBI:9008 (4)
CHEBI:15971 (4)
CHEBI:16704 (4)
CHEBI:16737 (4)
CHEBI:16347 (4)
CHEBI:15354 (4)
CHEBI:16643 (4)
CHEBI:17895 (4)
CHEBI:17596 (4)

Metabolite Name

Betaine (8)
L-Arginine (8)
Choline (8)
Uridine (8)
Hypoxanthine (8)
Methionine (7)
Adenosine (7)
Phosphorylcholine (7)
Linoleic acid (7)
Adenine (7)
Creatinine (7)
Uracil (6)
Pantothenic acid (6)
L-Histidine (6)
Creatine (6)
Glycerophosphocholine (6)
L-Carnitine (6)
L-Methionine (6)
Thiamine monophosphate (5)
N-Methylnicotinamide (5)
L-Norleucine (5)
PC(16:0/16:0) (5)
Heptadecanoic acid (5)
Thiamine (5)
L-Lysine (5)
5'-Methylthioadenosine (5)
L-Proline (5)
5-Methylcytosine (5)
Daidzein (5)
Indole (5)

First Public Date

2025 (259)
2026 (224)
2024 (211)
2023 (154)
2022 (149)
2014 (139)
2021 (117)
2020 (110)
2019 (100)
2017 (68)
2018 (65)
2016 (39)
2013 (37)
2015 (31)
2011 (6)
2012 (3)

Study status

Not provided (1)
Recruiting (1)

Lab affiliation

Chair of Parasite Molecular Biology Biological Chemistry and Drug Discovery, School of Life Sciences (3)
Cancer Center and Research Institute of Intestinal Diseases, Shanghai Tenth People's Hospital, School of Medicine, Tongji University (2)
Department of Genetic Medicine and Development, Faculty of Medicine, University of Geneva, Switzerland (2)
Department of Genome Sciences, University of Washington, Seattle, WA 98195 USA (2)
EDyP (2)
1. Center for Medical Biotechnology, VIB, Ghent, Belgium 2. Department for Biomolecular Medicine, Ghent University, Ghent, Belgium 3. VIB Proteomics Core, VIB, Ghent, Belgium (1)
1. Center for Medical Biotechnology, VIB, Ghent, Belgium. 2. Department for Biomolecular Medicine, Ghent University, Ghent, Belgium 3. VIB Proteomics Core, VIB, Ghent, Belgium (1)
1. St. Anna Children’s Cancer Research Institute (CCRI), Vienna, Austria 2. CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria 3. Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Vienna, Austria 4. Medical University of Vienna, Department of Pediatrics and Adolescent Medicine, Vienna, Austria 5. St. Anna Children’s Hospital, Medical University of Vienna, Department of Pediatrics and Adolescent Medicine, Vienna, Austria (1)
1Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada 2 Snyder Institute for Chronic Diseases, Hotchkiss Brain Institute and McCaig Institute for Bone and Joint Health, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada (1)
Acting Head of Proteomics (1)
Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (1)
Biochemical Proteomics Group, Department of Proteomics and Signal Transduction, Max-Planck Institute of Biochemistry, 82152-Martinsried, Germany (1)
Boston College (1)
CSIR-Institute of Genomics and Integrative Biology (1)
Calico Life Sciences (1)
Cambridge Institute for Therapeutic Immunology and Infectious Disease (CITIID), University of Cambridge, UK (1)
Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID), Jeffrey Cheah Biomedical Centre Cambridge Biomedical Campus, University of Cambridge, Cambridge, CB2 0AW, UK. (1)
Cambridge Institute of Therapeutic Immunology and Infectious Disease, Unveristy of Cambridge, UK (1)
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences Lazarettgasse 14, AKH BT 25.3 1090 Vienna, Austria (1)
Chemistry Department, The Scripps Research Institute, La Jolla, California, USA (1)
Dana Farber Cancer Institute: Dept. of Cancer Biology Harvard Medical School: Department of Cell Biology (1)
Department of Biological Sciences, Vanderbilt University, Nashville, TN 37212 (1)
Department of Biology University of Konstanz Germany (1)
Department of Biology, Institute of Microbiology, ETH Zürich, Switzerland (1)
Department of Biology, University of Konstanz, Universitaetsstrasse 10, 78457 Konstanz, Germany (1)
Department of Biology, Washington University in St. Louis, St. Louis, MO, USA (1)
Department of Biomedical Engineering, University of Wisconsin-Madison (1)
Department of Cellular and Molecular Pharmacology, QUantitative Bioscience Institute, University of California, San Francisco (1)
Department of Chemistry The Scripps Research Institute (1)
Department of Developmental Genetics, Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany (1)

Keyword

Industry (1)
Genetic (1)
Epidemiology (1)

Classification

bacteria (33)
fungi (19)
protozoa (6)
viruses (2)

Modification

2x(15)N labeled L-lysine (1)
4-tetrahydrothiazine-3-carboxylic acid (1)
4x(15)N labeled L-arginine (1)
N6-dimethyl-L-lysine (1)

Study type

Transcription profiling by array (773)
RNA-seq of coding RNA (195)
Unknown experiment type (54)
ChIP-seq (40)
DNA-seq (37)
Comparative genomic hybridization by array (36)
Other (27)
Methylation profiling by array (26)
RNA-seq of non coding RNA (26)
RNA-seq of coding RNA from single cells (14)
Methylation profiling by high throughput sequencing (12)
Cell line - High-throughput sequencing (11)
ChIP-chip by tiling array (10)
RNA-seq of total RNA (9)
ChIP-chip by array (7)
Genotyping by high throughput sequencing (7)
Animal - High-throughput sequencing (6)
Genotyping by array (6)
High-throughput sequencing (5)
Transcription profiling by tiling array (5)
Transcription profiling by RT-PCR (5)
Transcription profiling by SAGE (4)
MicroRNA profiling by array (3)
Proteomic profiling by array (3)
RNAi profiling by array (2)
CLIP-seq (2)
FAIRE-seq (1)
Tiling path by array (1)
MicroRNA profiling by high-throughput sequencing (1)
Human - High-throughput sequencing (1)

Release Date

2022 (642)
2023 (622)
2021 (593)
2025 (560)
2024 (506)
2020 (496)
2019 (445)
2015 (435)
2014 (431)
2016 (403)
2018 (402)
2013 (388)
2017 (382)
2010 (370)
2012 (327)
2011 (303)
2008 (212)
2009 (200)
2007 (120)
2026 (104)
2006 (86)
2005 (72)
2004 (40)
2003 (36)
2002 (36)
2001 (24)
1999 (24)
2000 (21)
1998 (12)
1997 (5)

Location

Australia (1)

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Natural genetic variation perturbs collaborative transcription factor binding required for enhancer selection and function

Natural genetic variation between two mouse strains was used as a natural mutagenesis screen to test various aspects of the proposed model for enhancer selection and function. Chromatin marks H3K4me2, H3K27Ac, and transcription factors PU.1, C/EBPa, and p65 were assessed by ChIP-Seq and GRO-Seq and ...

ORGANISM(S): Mus musculus

2013-10-15 | E-GEOD-46494 | biostudies-arrayexpress

In vivo screen of Francisella tularensis subsp. novicida mutants in sequence defined transposon library

We used an inhalation mouse model of infection to query a collection of 2149 mutants in a Francisella tularensis subsp. novicida background for genes required for growth, survival and systemic dissemination. A microarray-based genome-wide negative selection screen (Microarray tracking of transposon ...

ORGANISM(S): Francisella tularensis subsp. novicida

2008-12-30 | E-GEOD-11297 | biostudies-arrayexpress

Oligoarray comparative genomic hybridisation-mediated mapping of suppressors of an essential receptor tyrosine kinase generated in a deletion-biased mutagenesis screen

We have used oligoarray comparative genomic hybridization (aCGH) to identify novel suppressors generated in a UV-TMP based suppressor screen. This approach is suitable for detecting single gene mutations as well as copy number variations. Keywords: C.elegans Suppressor screen array CGH [1] 2 test s...

ORGANISM(S): Caenorhabditis elegans

2012-07-12 | E-GEOD-15224 | biostudies-arrayexpress

Genome-scale CRISPR knockout screen for a Dengue virus mutant

Unbiased forward genetic screen to identify host factors for a Dengue virus mutant

ORGANISM(S): Homo sapiens

2023-06-30 | E-MTAB-11119 | biostudies-arrayexpress

MDM33 overexpression suppressor screen

We performed a genome-wide screen for genetic MDM33 interaction partners. Using the opposite approach of the well known synthetic dosage lethality (screening for deletion strains in which a non-toxic overexpression is associated with a synthetic growth arrest) we screened the whole genome for genes ...

ORGANISM(S): Saccharomyces cerevisiae

2016-01-12 | E-GEOD-49580 | biostudies-arrayexpress

An RNAi Screen of Chromatin Proteins Identifies Tip60-p400 as a Regulator of Embryonic Stem Cell Identity

This SuperSeries is composed of the following subset Series: GSE11240: An RNAi Screen of Chromatin Proteins Identifies Tip60-p400 as a Regulator of Embryonic Stem Cell Identity, Experiment A GSE11241: An RNAi Screen of Chromatin Proteins Identifies Tip60-p400 as a Regulator of Embryonic Stem Cell Id...

ORGANISM(S): Mus musculus

2008-07-11 | E-GEOD-11243 | biostudies-arrayexpress

A genome-wide genetic interaction screen reveals metabolic roles of human histone deacetylase 1

Dynamic acetylation of metabolic proteins has emerged as a ubiquitous post-translational modification of human metabolic proteins. However, the corresponding modifying enzymes and the functions of the modification await exploration. Using a genome-wide synthetic lethality screen, we constructed a ge...

ORGANISM(S): Homo sapiens

2012-02-10 | E-GEOD-29662 | biostudies-arrayexpress

Tissue-specific genetic regulation of splicing and expression (gene-level)

Numerous genome-wide screens for polymorphisms that influence gene expression have provided key insights into the genetic control of transcription. Despite this work, the relevance of specific polymorphisms to in vivo expression and splicing remains unclear. We carried out the first genome-wide scre...

ORGANISM(S): Homo sapiens

2011-07-08 | E-GEOD-30453 | biostudies-arrayexpress

A forward genetic screen for regulators of muscle morphogenesis in Drosophila

PRJNA690537 | ENA

Systematic identification of G-quadruplex sensitive lethality by genome-wide genetic screening

A375 and HT1080 cells are treated with G-quadruplex ligands PDS or PhenDC3 following genome-wide shRNA knockdown. This enables the identification of genes that when silenced, specifically compromises cell growth in the presence of the ligand. First, a pilot screen was performed to determine a ligand...

ORGANISM(S): Homo sapiens

2019-06-22 | E-MTAB-6367 | biostudies-arrayexpress

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