Genetically engineered mice

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Mus musculus (391)
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Organisms

Mus musculus (405)
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mouse metagenome (1)
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Repository

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Disease

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Technology Type

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Instrument Platform

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Liquid Chromatography MS - positive - reverse phase (1)

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2013 (14)
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2010 (8)
2008 (5)
2007 (4)
2005 (1)
2004 (1)

CHEBI ID

CHEBI:165235 (1)
CHEBI:132767 (1)
CHEBI:192804 (1)
CHEBI:166577 (1)
CHEBI:173361 (1)
CHEBI:58349 (1)
CHEBI:88843 (1)
CHEBI:89731 (1)
CHEBI:192304 (1)
CHEBI:5445 (1)
CHEBI:6039 (1)
CHEBI:34856 (1)
CHEBI:4969 (1)
CHEBI:48991 (1)
CHEBI:19092 (1)
CHEBI:33020 (1)
CHEBI:17587 (1)
CHEBI:28717 (1)
CHEBI:45441 (1)
CHEBI:16070 (1)
CHEBI:73054 (1)
CHEBI:45713 (1)
CHEBI:17306 (1)
CHEBI:17992 (1)
CHEBI:15824 (1)
CHEBI:16857 (1)
CHEBI:17115 (1)
CHEBI:4828 (1)
CHEBI:146193 (1)
CHEBI:17295 (1)

Metabolite Name

C00049 (1)
Fumarylacetic acid (1)
(4'R£¬6R£¬6'S£¬7S£¬8R)-6'-(2-hydroxypentan-2-yl)-4'£¬8-dimethyldecahydro-5H-spiro[indolizine-6£¬2'-pyran]-7£¬8-diol (1)
Ethyl 3-Methyl-5-Methylpyrrole-2-Carboxylate (1)
Pentetrazol (1)
5-Acetyl-2£¬3-dihydro-1£¬4-thiazine (1)
Guanidinosuccinate (1)
HMDB0000511 (1)
7-hydroxychromen-2-one (1)
ACar 22:6 (1)
N-Acetylgalactosamine 6-sulfate (1)
Methyl benzoate (1)
2'-Deoxyadenosine (1)
Alpha-Hydroxyisobutyric acid (1)
N-Acetyl-a-neuraminic acid (1)
(-)-5-(2-Propenyl)-2-oxazolidinethione (1)
2-Propionyl-2-thiazoline (1)
3-Phenylpropyl acetate (1)
O-propanoyl-carnitine (1)
D-Fructose (1)
Beta-Alanine (1)
Resveratrol (1)
Pyruvic acid (1)
Pelargonic acid (1)
Tetraethylene glycol (1)
Methyltyrosinate (1)
Byssochlamic Acid (1)
L-Gulonolactone (1)
N-Glycolylneuraminic acid (1)
Lumichrome (1)

First Public Date

2025 (93)
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Classification

bacteria (1)

Study type

Transcription profiling by array (80)
RNA-seq of coding RNA (17)
ChIP-seq (9)
Comparative genomic hybridization by array (7)
DNA-seq (6)
RNA-seq of coding RNA from single cells (4)
Cell line - High-throughput sequencing (3)
Methylation profiling by high throughput sequencing (3)
Transcription profiling by RT-PCR (2)
Unknown experiment type (1)
High-throughput sequencing (1)
Animal - High-throughput sequencing (1)
ChIP-chip by array (1)
Genotyping by array (1)
Bisulfite-seq (1)
ATAC-seq (1)
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Release Date

2021 (119)
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2013 (53)
2011 (40)
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2009 (34)
2008 (30)
2026 (28)
2010 (25)
2007 (13)
2004 (5)
2006 (5)
2005 (4)
2003 (2)
2002 (1)
2001 (1)
2000 (1)
1998 (1)
1997 (1)

Lab affiliation

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA (2)
Deputy Head (Research), Department of Biochemistry and Molecular Biology Head Immunoproteomics Laboratory Infection and Immunity Program Room 214, level 2, 15 Innovation Walk Monash Biomedicine Discovery Institute Monash University, Clayton Campus Clayton 3800 Victoria Australia (2)
CRUK -CRUK Scotland nstitute for Cancer Research - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (2)
Centre de Recherche en Cancérologie de Marseille (CRCM) Inserm U1068 - CNRS UMR7258 - Institut Paoli-Calmettes - Aix-Marseille Université Campus de Luminy, Case 915, 163 Avenue de Luminy 13288 Marseille Cedex 9 - FRANCE (1)
Laboratoire de Génétique Ophtalmologique, INSERM U1163, Institut Imagine, Paris, France (1)
Gladstone Institute of Neurological Disease, San Francisco, CA, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA, USA; Bakar Aging Research Institute, University of California, San Francisco, San Francisco, CA, USA. (1)
Assistant Professor, Neurology University of California, San Francisco (1)
Department of Molecular and Cellular Oncology, MD Anderson Cancer Center, Houston, TX USA (1)
College of Chemistry and Molecular Engineering, Peking University, Beijing, China (1)
Department of Pediatrics Indiana University School of Medicine Riley Hospital for Children (1)
Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany (1)
Beth Israel Deaconess Medical Center, Harvard Medical School Boston MA 02215 United States (1)
Lab for Retinal Cell Biology Dept. Ophthalmology USZ / UZH University of Zurich (1)
Spanish National Cancer Research Center (CNIO) (1)
Post Graduate Program in Dentistry, Cruzeiro do Sul University, SãoPaulo, Brazil; Hospital Israelita Albert Einstein, São Paulo, Brazil; Department of Oral Biology, School of Dental Medicine, The University of Buffalo, State University of New 17 York, Buffalo, NY, USA (1)
CNIC (1)
CRUK -CRUK Scotland Institute for Cancer Research - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (1)
National Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (1)
Indiana University School of Medicine (1)

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Francisella tularensis subsp. tularensis strain:genetically engineered

Francisella tularensis subsp. tularensis strain:genetically engineered Genome sequencing

PRJNA1040318 | ENA

Fundamental differences in promoter CpG island DNA hypermethylation between human cancer and genetically engineered mouse models of cancer [RRBS]

Genetic and epigenetic alterations are essential for the initiation and progression of human cancer. We previously reported that primary human medulloblastomas showed extensive cancer-specific CpG island DNA hypermethylation in critical developmental pathways. To determine whether genetically engine...

ORGANISM(S): Mus musculus

2013-10-10 | E-GEOD-45341 | biostudies-arrayexpress

Fundamental differences in promoter CpG island DNA hypermethylation between human cancer and genetically engineered mouse models of cancer [Methylation profiling by array]

ORGANISM(S): Homo sapiens

2013-10-10 | E-GEOD-45240 | biostudies-arrayexpress

Predicting drug responsiveness in humans cancers using genetically engineered mice

Anti-cancer drug testing is challenging, but genetically engineered mouse models (GEMMs) and orthotopic, syngeneic transplants (OSTs) may offer advantages for pre-clinical testing including an intact microenvironment. We examined the efficacy of six chemotherapeutic or targeted anti-cancer drugs, al...

ORGANISM(S): Mus musculus

2014-01-01 | E-GEOD-37915 | biostudies-arrayexpress

Transcriptomic profiling of genetically engineered mouse tumors using SOCRATES

This dataset contains single-cell RNA sequencing data from murine colorectal tumors engineered using the SOCRATES platform, a CRISPR-based multiplex genome engineering system. Tumors were initiated in genetically engineered mouse models via lentiviral delivery of pooled sgRNAs targeting key driver g...

ORGANISM(S): Mus musculus

2026-05-01 | E-MTAB-15044 | biostudies-arrayexpress

LC-MS based untargeted metabolomics of muscle in GMPPB mutant mice

Muscle tissues from GMPPB mutant mouse model and control mice were collected, untargeted metabolomics was performed via LC-MS (positive/negative HILIC), differential metabolites were identified to explore the mechanismof GMPPB in muscular dystrophy.

2026-02-03 | MTBLS10214 | MetaboLights

Transcriptomic characterization of sotorasib-resistant tumors in Kras-G12C/Trp53-driven LUAD in genetically engineered mice

PRJNA842081 | ENA

Transcription profiling of synovial sarcoma-like tumors induced in a genetically engineered mouse model

Synovial sarcoma-like tumors were generated in mice by conditionally expressing the human t(X;18) translocation-derived SYT-SSX2 fusion protein. Using a Tamoxifen-inducible CreER system, we show here that sporadic expression of SYT-SSX2 across multiple tissue types leads to exclusive formation of sy...

ORGANISM(S): Mus musculus

2009-04-24 | E-GEOD-14469 | biostudies-arrayexpress

Transcriptomic Classification of Genetically Engineered Mouse Models of Breast Carcinoma Identifies Human Subtype Counterparts

Background: Human breast cancer is a heterogeneous disease consisting of multiple molecular subtypes. Genetically engineered mouse models (GEMMs) are useful resources for studying breast cancers in vivo under genetically controlled and immune competent conditions. Identifying murine models with cons...

ORGANISM(S): Mus musculus

2013-11-04 | E-GEOD-42640 | biostudies-arrayexpress

RNA-Seq of genetically engineered mouse model of Epithelioid Hemangioendothelioma tumors

PRJNA707561 | ENA

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2360 Results

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