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TranscriptomicsTranscription profiling of Renal Cell carcinoma cell lines following global de-methylation.
Promoter region hypermethylation and transcriptional silencing is a frequent cause of tumour suppressor gene (TSG) inactivation in many types of human cancers. Functional epigenetic studies, in which gene expression is induced by treatment with demethylating agents, may identify novel genes with tum...
ORGANISM(S): Homo sapiens 
2010-07-29 | E-GEOD-22563 | biostudies-arrayexpress
GenomicsDetection of chromatin accessibility in WT and SRC-2-/- mice in liver
We futher characterized genome-wide chromatin accessibility of WT and SRC-2-/- mouse liver at CT10 through DNase-Seq. In addition,chromatin accessibility was significantly reduced in SRC-2-/- mouse liver compared to WT mice at CT10. DNase-Seq was carried out in WT and SRC-2-/- mice in liver at CT10...
ORGANISM(S): Mus musculus 
2015-12-07 | E-GEOD-67859 | biostudies-arrayexpress
GenomicsCoactivator-Dependent Oscillation of Chromatin Accessibility Dictates Circadian Gene Amplitude through REV-ERB Loading
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2015-12-07 | E-GEOD-67860 | biostudies-arrayexpress
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