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TranscriptomicsTranscription profiling of brain, liver and spleen from rats infected with Escherichia coli K1 and treated with capsule-selective endosialidase E
Transcription profiling of infected and treated (Capsule-Selective Endosialidase E Minimizes) of RNA isolated from brain/spleen/liver of rats with E.coli K1
ORGANISM(S): Rattus norvegicus 
2010-01-10 | E-MEXP-2406 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of P. aeruginosa biofilms treated with tobramycin grown on CFBE41o- cells
We grew Pseudomonas aeruginosa biofilms on CFBE41o- human airway cells in culture, and we treated these biofilms with tobramycin. Microarray analysis was performed to gain an understanding of the global transcriptional changes that occur during antibiotic treatment. Experiment Overall Design: We co...
ORGANISM(S): Pseudomonas aeruginosa 
2008-06-18 | E-GEOD-9989 | biostudies-arrayexpress
TranscriptomicsGenome-wide transcriptomic profiling of Anopheles gambiae hemocytes reveals pathogen-specific signatures upon bacterial challenge and Plasmodium berghei infection
Background: The mosquito Anopheles gambiae is a major vector of human malaria. Increasing evidence indicates that blood cells (hemocytes) comprise an essential arm of the mosquito innate immune response against both bacteria and malaria parasites. To further characterize the role of hemocytes in mos...
ORGANISM(S): Anopheles gambiae 
2011-10-31 | E-GEOD-33269 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Pseudomonas aeruginosa treated with tobramycin
This SuperSeries is composed of the following subset Series:; GSE9989: Tobramycin Treatment of P. aeruginosa Biofilms Grown on CFBE41o- Cells; GSE9991: Tobramycin Treatment of Planktonic Pseudomonas aeruginosa Experiment Overall Design: Refer to individual Series
ORGANISM(S): Pseudomonas aeruginosa 
2008-06-18 | E-GEOD-10030 | biostudies-arrayexpress
UnknownPolybrominated diphenyl ethers (PBDEs) and hydroxylated PBDE metabolites (OH-PBDEs) in maternal and fetal tissues, and associations with fetal cytochrome P450 gene expression.
Not available
S-EPMC6561508 | biostudies-literature
TranscriptomicsPathway simulations in common oncogenic drivers of leukemic and rhabdomyosarcomatic cells: a systems biology approach
A part of current research has intensively been focused on the proliferation and metabolic processes governing biological systems. Since the advent of high throughput methodologies like microarrays, the load of genomic data has increased geometrically and along with that the need for computational m...
ORGANISM(S): Homo sapiens 
2011-12-20 | E-GEOD-34522 | biostudies-arrayexpress
TranscriptomicsRNA from 3 d and 2 d old embryos of mibta52b, mibm132 and mibtfi91, and RNA from 3 d, 2d and 1 d old embryos of mibta52b
The Notch signaling is an evolutionarily conserved signal transduction cascade that plays essential roles in a variety of developmental processes. In this study, we examined the mib mutants for defects in pancreas development using in situ hybridization and GFP expression analysis of pancreas-specif...
ORGANISM(S): Danio rerio 
2010-06-25 | E-GEOD-8522 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat testis by transplacental exposure to estrogen receptor (ER) agonists - high and low doses of 17a-Ethynyl estradiol, genistein or bisphenol A
The purpose of this study was to determine 1) the transcriptional program elicited by exposure to three estrogen receptor (ER) agonists: 17 a-ethynyl estradiol (EE), genistein (Ges) and bisphenol A (BPA) during fetal development of the rat testis and epididymis; and 2) whether very low dosages of es...
ORGANISM(S): Rattus norvegicus 
2005-05-18 | E-TABM-12 | biostudies-arrayexpress
UnknownGenotype-specific features reduce the susceptibility of South American yellow fever virus strains to vaccine-induced antibodies.
Not available
S-EPMC10067022 | biostudies-literature
GenomicsComprehensive genomic profiles of small cell lung cancer
We have sequenced the genomes of 110 small cell lung cancers (SCLC), one of the deadliest human cancers. We found bi-allelic inactivation of TP53 and RB1 in nearly all the tumors analyzed, sometimes by complex genomic rearrangements. Two tumors with wild-type RB1 had evidence of chromothripsis leadi...
EGAS00001000925 | EGA
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