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MetabolomicsMitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis
Somatic DNMT3A R882 codon mutations drive the most common form of clonal haematopoiesis (CH) and are associated with increased acute myeloid leukaemia (AML) risk1,2. Preventing expansion of DNMT3A-R882-mutant haematopoietic stem/progenitor cells (HSPCs) may therefore avert progression to AML. To ide...
2025-02-06 | MTBLS12201 | MetaboLights
UnknownWide Variation In Differences In Resource Use Seen Across Conditions Between Medicare Advantage, Traditional Medicare.
Not available
S-EPMC11982645 | biostudies-literature
TranscriptomicsBRACHYURY knockdown in differentiating hESCs
Transcriptional profiling of H9 hESCs (wild type and BRACHYURY shRNA knockdown) differentiated for 36h or 72h in chemically-defined culture media supplemented with FGF2, LY294002 and either BMP4 or ActivinA.
ORGANISM(S): Homo sapiens 
2015-05-19 | E-MTAB-2912 | biostudies-arrayexpress
UnknownManagement of glenohumeral osteoarthritis in the younger patient: A population level analysis of usual care delivery in a large health system.
Not available
S-EPMC12671371 | biostudies-literature
UnknownPhylogenetic, genomic, and biogeographic characterization of a novel and ubiquitous marine invertebrate-associated Rickettsiales parasite, Candidatus Aquarickettsia rohweri, gen. nov., sp. nov.
Not available
S-EPMC6863919 | biostudies-literature
UnknownAssessment of Dietary Sodium Intake Using the Scored Salt Questionnaire in Autosomal Dominant Polycystic Kidney Disease.
Not available
S-EPMC7692491 | biostudies-literature
TranscriptomicsTranscriptome sequencing of nasopharyngeal carcinoma model system (miRNA)
Nasopharyngeal carcinoma (NPC) is a prevalent malignancyt disease in Southeast Asia among the Chinese population. Aberrant regulation of transcripts has been implicated in many types of cancers including NPC. Herein, we characterized mRNA and miRNA transcriptomes by RNA sequencing (RNASeq) of NPC mo...
ORGANISM(S): Homo sapiens 
2014-02-05 | E-GEOD-54161 | biostudies-arrayexpress
TranscriptomicsTranscriptome sequencing of nasopharyngeal carcinoma model system (mRNA)
Nasopharyngeal carcinoma (NPC) is a prevalent malignancyt disease in Southeast Asia among the Chinese population. Aberrant regulation of transcripts has been implicated in many types of cancers including NPC. Herein, we characterized mRNA and miRNA transcriptomes by RNA sequencing (RNASeq) of NPC mo...
ORGANISM(S): Homo sapiens 
2014-02-05 | E-GEOD-54159 | biostudies-arrayexpress
TranscriptomicsMLL Fusion Proteins Preferentially Regulate a Small Set of Wild Type MLL Target Genes in the Leukemic Genome
MLL encodes a histone methyltransferase that is critical in maintaining gene expression during embryonic development and hematopoiesis. 11q23 translocations encode chimeric MLL fusions that act as potent drivers of acute leukemia. However, it remains unclear what portion of the leukemic genome is un...
ORGANISM(S): Mus musculus 
2011-04-28 | E-GEOD-24794 | biostudies-arrayexpress
UnknownThe Global Kidney Patient Trials Network and the CAPTIVATE Platform Clinical Trial Design: A Trial Protocol.
Not available
S-EPMC11635535 | biostudies-literature
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