Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of E47 targets in the neuroblastoma cell line SK-N-SH at 8 hours and 20 hours
E47 is a basic Helix Loop Helix (bHLH) transcription factor that has important roles in cell fate determination and differentiation of many cell types. In the nervous system E47 heterodimerizes with tissue-specific, pro-neural bHLH transcription factors and activates downstream target genes. To iden...
ORGANISM(S): Homo sapiens 
2006-02-01 | E-MEXP-413 | biostudies-arrayexpress
TranscriptomicsSusceptibility to DNA damage as a molecular mechanism for non-syndromic cleft lip and palate
Non-syndromic cleft lip/palate (NSCL/P) is a complex, frequent congenital malformation, determined by the interplay between genetic and environmental factors during embryonic development. Previous findings have appointed an aetiological overlap between NSCL/P and cancer, and alterations in similar b...
ORGANISM(S): Homo sapiens 
2014-01-01 | E-GEOD-42589 | biostudies-arrayexpress
UnknownSocioeconomic Factors and Survival of Multiple Myeloma Patients.
Not available
S-EPMC7913279 | biostudies-literature
UnknownPhase I clinical trial of O6-benzylguanine and topical carmustine in the treatment of cutaneous T-cell lymphoma, mycosis fungoides type.
Not available
S-EPMC3519426 | biostudies-literature
UnknownA phase 1 study of TRC102, an inhibitor of base excision repair, and pemetrexed in patients with advanced solid tumors.
Not available
S-EPMC6662598 | biostudies-literature
UnknownTumor-selective use of DNA base excision repair inhibition in pancreatic cancer using the NQO1 bioactivatable drug, β-lapachone.
Not available
S-EPMC4658501 | biostudies-literature
TranscriptomicsEarly gene expression changes in spinal cord from SOD1G93A Amyotrophic Lateral Sclerosis animal model
Amyotrophic Lateral Sclerosis (ALS) is an adult-onset and fast progression neurodegenerative disease that leads to the loss of motor neurons. Mechanisms of selective motor neuron loss in ALS are unknown. The early events occurring in the spinal cord that may contribute to motor neuron death are not ...
ORGANISM(S): Mus musculus 
2013-11-21 | E-GEOD-50642 | biostudies-arrayexpress
TranscriptomicsGene expression profile in sciatic nerve from presymptomatic SOD1G93A Amyotrophic Lateral Sclerosis animal model revealed potential non-autonomous involvement of Schwann cells
Microarray analyses using a whole mouse genome platform were employed in the evaluation of gene expression pattern of sciatic nerves of transgenic SOD1(G93A) mice and their littermate controls at presymptomatic age of 60 days Sciatic nerve from SOD1G93A and Non transgenic controls from 60 days were ...
ORGANISM(S): Mus musculus 
2015-06-04 | E-GEOD-69450 | biostudies-arrayexpress
TranscriptomicsDeregulated expression of cytoskeleton related genes in the spinal cord and sciatic nerve of presymptomatic SOD1G93A Amyotrophic Lateral Sclerosis mouse model
Early molecular events related to cytoskeleton are poorly described in Amyotrophic Lateral Sclerosis (ALS), especially in the Schwann cell (SC), which offers strong trophic support to motor neurons. DAVID tool identified cytoskeleton-related genes by employing the Cellular Component of Gene Ontology...
ORGANISM(S): Mus musculus 
2014-04-22 | E-GEOD-56926 | biostudies-arrayexpress
TranscriptomicsA Small RNA-Catalytic Argonaute Pathway Tunes Germline Transcript Levels to Ensure Embryonic Divisions
Multiple division cycles without growth are a characteristic feature of early embryogenesis. The female germline deposits proteins and RNAs into oocytes to support these divisions, which lack many of the quality control mechanisms operating in somatic cells undergoing growth. How the composition of ...
ORGANISM(S): Caenorhabditis elegans 
2016-03-24 | E-GEOD-75128 | biostudies-arrayexpress
Sort   by:  
 Page size