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TranscriptomicsAn EMT-driven alternative splicing program occurs in human breast cancer and modulates cellular phenotype.
Regulation of cell-cell junction formation and regulation of cell migration were enriched among EMT (Epithelial-Mesenchymal Transition)-associated alternatively splicing events. Our analysis suggested that most EMT-associated alternative splicing events are regulated by one or more members of the RB...
ORGANISM(S): Homo sapiens 
2011-07-15 | E-GEOD-30290 | biostudies-arrayexpress
TranscriptomicsRNAi profiling of mouse loss of function mutant using in vivo screening identifies regulators of actin dynamics as key determinants of lymphoma progression
Mouse models have dramatically improved our understanding of cancer development and tumor biology. However, these models have shown limited efficacy as tractable systems for unbiased genetic experimentation. Here, we report the adaptation of loss of function screening to mouse models of cancer. U...
ORGANISM(S): Mus musculus 
2009-09-23 | E-GEOD-16090 | biostudies-arrayexpress
UnknownMena binds α5 integrin directly and modulates α5β1 function
Not available
S-JCBD-201202079 | bioimages
UnknownThe inositol 5-phosphatase SHIP2 regulates endocytic clathrin-coated pit dynamics
Not available
S-JCBD-201005018 | bioimages
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