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ProteomicsLncRNA EPR-induced METTL7A1 modulates target gene translation
EPR is a long non-coding RNA (lncRNA) that controls cell proliferation in mammary gland cells by regulating gene transcription. Here, we report on Mettl7a1 as a direct target of EPR. We show that EPR induces Mettl7a1 transcription by rewiring three-dimensional chromatin interactions at the Mettl7a1 ...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-12 | PXD034398 | Pride
Lncerna Rna binding protein Translation 
TranscriptomicsDestabilization of Nucleophosmin mRNA by the HuR/KSRP complex is required for muscle fiber formation
HuR promotes myogenesis by stabilizing MyoD, Myogenin and p21 mRNAs during the fusion step of muscle cells to form myotubes. Here we show that HuR, via a novel mRNA destabilizing activity, promotes the early steps of myogenesis by reducing the expression of the cell cycle promoter nucleophosmin (NPM...
ORGANISM(S): Mus musculus 
2014-04-26 | E-GEOD-57113 | biostudies-arrayexpress
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