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TranscriptomicsMicroRNA-150 Contributes to the Proficiency of B-Cell Receptor Signaling in Chronic Lymphocytic Leukemia by Regulating Expression of GAB1 and FOXP1 Genes
We examined the microRNAs (miRNAs) expressed in chronic lymphocytic leukemia (CLL) and identified miR-150 as the most abundant, but with leukemia-cell-expression levels that varied among patients. CLL cells that expressed ZAP-70 or that used unmutated IGHV each had a median expression-level of miR-1...
ORGANISM(S): Homo sapiens 
2014-08-04 | E-GEOD-49896 | biostudies-arrayexpress
TranscriptomicsROR1 Can Interact With TCL1 And Enhance Leukemogenesis in EM-BM-5-TCL1 Transgenic Mice
Transcriptome analysis of RNA samples from leukemia cells of ROR1xTCL1 and TCL1 transgenic mice Animals engrafted with ROR1xTCL1 leukemia-cells developed more aggressive disease than mice engrafted with TCL1 leukemia cells. Transcriptome analysis of RNA samples from leukemia ROR1xTCL1 transgenic mi...
ORGANISM(S): Mus musculus 
2014-01-02 | E-GEOD-51420 | biostudies-arrayexpress
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