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TranscriptomicsTranscription profiling of rat liver after Ghrelin treatment and bile duct ligation
Hepatic fibrosis, the wound-healing response to repeated liver injury, ultimately leads to cirrhosis. There is an urgent need to develop effective antifibrotic therapies. Ghrelin (encoded by Ghrl) is an orexigenic hormone that has pleiotrophic functions including protection against cell death1. Here...
ORGANISM(S): Rattus norvegicus 
2009-01-13 | E-GEOD-13747 | biostudies-arrayexpress
TranscriptomicsWhole transcriptome analysis of pancreatic ghrelin cells in WT and Nkx2.2 KO mouse embryo
Whole transcriptome analysis of Ghrelin-expressing and -descendant cells in pancreas from Nkx2.2 KO and WT mouse embryos.
ORGANISM(S): Mus musculus 
2015-02-25 | E-MTAB-3353 | biostudies-arrayexpress
GenomicsGhrelin deletion and conditional ghrelin-cell ablation increase pancreatic islet size in mice
Ghrelin deletion and conditional ghrelin-cell ablation increase pancreatic islet size in mice
PRJNA1022509 | ENA
TranscriptomicsHippocampal gene expression from acyl-ghrelin treated mice
Ghsr-/- mice and WT controls (14 weeks-old, n = 3 / group) were used to analyse whole genome gene expression in the hippocampal DG. Briefly, mice were prepared with jugular vein cannulae attached to osmotic mini-pumps (Alzet model 2001) under isofluorane anesthesia. The mini-pumps delivered either v...
ORGANISM(S): Mus musculus 
2022-11-01 | E-MTAB-3601 | biostudies-arrayexpress
TranscriptomicsUnacylated Ghrelin Rapidly Modulates Lipogenic and Insulin Signaling Pathway Gene Expression in Metabolically Active Tissues of GHSR Deleted Mice
Background: There is increasing evidence that unacylated ghrelin (UAG) improves insulin sensitivity and glucose homeostasis; however, the mechanism for this activity is not fully understood since a UAG receptor has not been discovered. Methodology/Principal Findings: To assess potential mechanisms o...
ORGANISM(S): Mus musculus 
2010-07-29 | E-GEOD-22506 | biostudies-arrayexpress
UnknownToward a consensus nomenclature for ghrelin, its non-acylated form, liver expressed antimicrobial peptide 2 and growth hormone secretagogue receptor.
Not available
S-EPMC10078427 | biostudies-literature
TranscriptomicsTranscription profiling of rat epididymal and retroperitoneal fat
Comparison of gene expression profiles from epididymal and retroperitoneal fat in adult male SD rats.
ORGANISM(S): Rattus norvegicus 
2009-05-30 | E-MEXP-1993 | biostudies-arrayexpress
TranscriptomicsGhrelin deletion and conditional ghrelin-cell ablation increase pancreatic islet size in mice
We utilized single cell sequencing of FACS sorted cells from pancreatic islets of wildtype and ghrelin knock out mice to understand the effects of ghrelin deletion on gene expression profiles of various islet cells.
ORGANISM(S): Mus musculus 
2023-11-06 | GSE244390 | GEO
GenomicsWhole ovaries RNA sequencing WT and ghrelin o-acyltransferase (GOAT) knockout mice
Whole ovaries RNA sequencing WT and ghrelin o-acyltransferase (GOAT) knockout mice
PRJNA416334 | ENA
TranscriptomicsChitosan-affected gene expression profiles in brain and stomach
Chitosan has been widely used in food industry as a weight-loss aid and a cholesterol-lowering agent. Previous studies have shown that chitosan affects metabolic responses and contributes to anti-diabetic, hypocholestermic, and blood glucose-lowering effects; however, the in vivo targeting sites and...
ORGANISM(S): Mus musculus 
2014-10-29 | E-GEOD-33565 | biostudies-arrayexpress
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