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Cell types are fundamental units of metazoans, however their definition remains a long-standing challenge. We here use high throughput assays allowing for unprecedented resolution and systematic analyses. The comparison of the transcriptional landscapes of related and unrelated Drosophila differenti...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2026-04-27 | PXD056082 | Pride
Hemocytes were sorted from stage 16 embryos and wandering 3rd instar larvae in which gcm was knocked down using gcmRNAi and the driver srp(hemo)Gal4. The experiments were done in triplicate. The wild type controls at stage 16 embryo and wandering larvae are available under this assession number: E-M...
ORGANISM(S): Drosophila melanogaster 
The aim of this experiment is to compare the transcriptome of Drosophila hemocytes at two developmental stages: in stage 16 embryo, mostly free from any immune challenge and in larvae, which grow in bacteria rich environment. Transgenes inducing the expression of RFP in the hemocytes were used to so...
ORGANISM(S): Drosophila melanogaster 
We aimed at characterizing the diverse hemocyte populations present in the hemolymph of the Drosophila larvae. The hemocytes were collected from wandering larvae infested by wasp (WI) or not infested (NI). The hemocytes were then sequenced using 10x genomics technology.
ORGANISM(S): Drosophila melanogaster 
The aim of the experiment is to establish the impact of the interaction between the hemocyte differentiation factor gcm and the Toll pathway in the immune cells of the Drosophila larva. The hemocytes were collected from 3rd instar larvae of the following genotypes: Toll10B/+, gcm26/+ and gcm26/+;Tol...
ORGANISM(S): Drosophila melanogaster 
We produced bulk RNA sequencing data on Drosophila neurons, glia and hemocytes at embryonic and larval stages to extrapolate the most significant and specific features that identify a cell type as a whole. We also tracked changes in the expression in the two stages. We identified stable features tha...
ORGANISM(S): Drosophila melanogaster 
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