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UnknownHotspots and frontiers of the relationship between hepatocellular carcinoma and cancer-associated fibroblasts: a bibliometric analysis and review.

Background

Cancer-associated fibroblasts (CAFs) are pivotal stromal components in the tumor microenvironment (TME) of hepatocellular carcinoma (HCC), influencing tumor progression, metastasis, and immunotherapy resistance. However, a comprehensive bibliometric overview of CAFs in HCC is lack...
S-EPMC12830541 | biostudies-literature
UnknownAngiopoietin-2 and the Vascular Endothelial Growth Factor Promote Migration and Invasion in Hepatocellular Carcinoma- and Intrahepatic Cholangiocarcinoma-Derived Spheroids.
Aggressive hepatocellular carcinoma (HCC) overexpressing Angiopoietin-2 (ANG-2) (a protein linked with angiogenesis, proliferation, and epithelial-mesenchymal transition (EMT)), shares 95% of up-regulated genes and a similar poor prognosis with the proliferative subgroup of intrahepatic cholangiocar...
S-EPMC10813100 | biostudies-literature
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