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TranscriptomicsMicroRNA expression in prostate cancer cells stimulated with cancer associated fibroblasts
Tumor microenvironment is a strong determinant for the acquisition of metastatic potential of cancer cells. It has been demonstrated (Giannoni E et al., Cancer Res 2010) that cancer associated fibroblasts (CAF) elicit an epithelial-mesenchymal transition (EMT) in prostate cancer (PCa) cells, leading...
ORGANISM(S): Homo sapiens 
2013-09-01 | E-GEOD-42699 | biostudies-arrayexpress
TranscriptomicsMesenchymal to amoeboid transition is associated with stem-like features of melanoma cells
Cellular plasticity confers cancer cells the ability to adapt to micro-environmental changes, a fundamental requirement for tumour progression and metastasis. The epithelial to mesenchymal transition (EMT) is a transcriptional programme associated with increased cell motility and stemness. Beside EM...
ORGANISM(S): Homo sapiens 
2014-04-22 | E-GEOD-52246 | biostudies-arrayexpress
TranscriptomicsDemethyl fructiculin A (SCO-1) induces apoptosis by inducing reactive oxygen species in mitochondria
Demethyl fructiculin A is a diterpenoid quinone component of the exudates from Salvia corrugata (SCO-1) leafes. SCO-1 was recently reported to induce anoikis in mammalian cell lines via a molecular mechanism involving the presence of the membrane scavenging receptor CD36. However, experiments perfor...
ORGANISM(S): Homo sapiens 
2010-10-15 | E-GEOD-19846 | biostudies-arrayexpress
UnknownUnveiling a sudden unexplained death case by whole exome sequencing and bioinformatic analysis.
Not available
S-EPMC7196487 | biostudies-literature
UnknownWhole-exome sequencing to identify causative variants in juvenile sudden cardiac death.
Not available
S-EPMC11407015 | biostudies-literature
TranscriptomicsIntegrated miRNA and gene expression analysis of prostate cancer associated fibroblasts supports a prominent role for interleukin-6 in fibroblast activation [gene]
Tumor microenvironment coevolves with and simultaneously sustains cancer progression. Reactive fibroblasts found in prostate cancer (PCa), known as cancer associated fibroblasts (CAF), have been indeed shown to fuel tumor development and metastasis by mutually interacting with PCa cells. Little is k...
ORGANISM(S): Homo sapiens 
2015-09-01 | E-GEOD-68164 | biostudies-arrayexpress
TranscriptomicsIntegrated miRNA and gene expression analysis of prostate cancer associated fibroblasts supports a prominent role for interleukin-6 in fibroblast activation [miRNA]
Tumor microenvironment coevolves with and simultaneously sustains cancer progression. Reactive fibroblasts found in prostate cancer (PCa), known as cancer associated fibroblasts (CAF), have been indeed shown to fuel tumor development and metastasis by mutually interacting with PCa cells. Little is k...
ORGANISM(S): Homo sapiens 
2015-09-01 | E-GEOD-68165 | biostudies-arrayexpress
UnknownDeformation Imaging by Strain in Chronic Heart Failure Over Sacubitril-Valsartan: A Multicenter Echocardiographic Registry.
Not available
S-EPMC10053272 | biostudies-literature
UnknownSacubitril/valsartan reduces indications for arrhythmic primary prevention in heart failure with reduced ejection fraction: insights from DISCOVER-ARNI, a multicenter Italian register.
Not available
S-EPMC9242049 | biostudies-literature
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