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MetabolomicsGiardiavirus infection mediates Enolase to the upregulation of Glycolysis in Giardia

Giardia duodenalis is a prevalent intestinal parasite that cause giardiasis, a condition characterized by diarrhea and frequently linked to malnutrition and growth impairments in children. The presence of Giardiavirus (GLV) can lead to reduced pathological damage in mice infected with Giardia and...

2025-07-05 | MTBLS12615 | MetaboLights
MetabolomicsEffects of Giardia intestinalis on mice GI tract
Not available
ORGANISM(S): Mus musculus 
ST000332 | MetabolomicsWorkbench
TranscriptomicsExpression data from the commensal bacteria Escherchia coli strain HB101 interacting with Caenorhabditis elegans and/or Giardia duodenalis
Homeostatic interactions between the host and its resident microbiota is important for normal physiological functions and if altered, it could lead to dysbiosis, a change in the structure and function of the microbiota, and as a result to various pathophysiologies. Altered structure in bacterial com...
ORGANISM(S): Escherichia coli 
2015-04-02 | E-GEOD-61092 | biostudies-arrayexpress
ProteomicsPeptidylarginine Deiminase inhibition abolishes the production of large extracellular vesicles from Giardia intestinalis, affecting host-pathogen interactions by hindering adhesion to host cells
Giardia intestinalis is a microaerophilic protozoan that is an important etiologic agent of diarrhea worldwide. There is evidence that under diverse conditions, the parasite is capable of shedding extracellular vesicles (EVs) which modulate the physiopathology of giardiasis. Here we describe new fea...
ORGANISM(S): Giardia 
2020-09-21 | PXD018460 | Pride
Host-pathogen interaction Giardia intestinalis Cannabidiol (cbd) Peptidylarginine deiminase inhibitor Extracellular vesicles 
ProteomicsIncomplete cytosolic iron-sulfur cluster assembly machinery of Giardia intestinalis is partially associated with mitosomes
Iron - sul fur (Fe -S) clusters are essential cofactors that enable proteins to transport electrons , sense signals or catalyze chemical reactions . The maturation of dozens of Fe - S proteins in various compartments of every eukaryotic cell is driven by several assembly pathways. The ubiquitous cyt...
ORGANISM(S): Giardia intestinalis assemblage A 
2016-09-29 | PXD004722 | Pride
Lc ms Giardi intestinalis 
TranscriptomicsAnalysis of the Transcriptomes of Giardia intestinalis Assemblages A, B and E Using Strand-specific RNA-seq
We have performed strand-specific RNA-seq of trophozoites from four different Giardia intestinalis strains (A=WB and AS175, B=GS, E=P15). Comparison of mRNA levels in four different Giardia intestinalis strains.
ORGANISM(S): Giardia intestinalis 
2013-03-28 | E-GEOD-36490 | biostudies-arrayexpress
TranscriptomicsGiardia lamblia WB: 5'5npac control vs. pPPax2
Transcriptional profiling of Giardia lamblia WB comparing control 5'5npac cells with pPPax2 cells. Two-condition experiment 5'5npac cells with pPPax2 cells.
ORGANISM(S): Giardia intestinalis 
2012-12-01 | E-GEOD-30875 | biostudies-arrayexpress
TranscriptomicsGiardia lamblia WB: 5'5npac control vs pPTopoII
Transcriptional profiling of Giardia lamblia WB comparing control 5'5npac cells with pPTopoII cells. Two-condition experiment 5'5npac cells with pPTopoII cells.
ORGANISM(S): Giardia intestinalis 
2013-06-30 | E-GEOD-39665 | biostudies-arrayexpress
TranscriptomicsCOMPARISON OF THE GIARDIA LAMBLIA TROPHOZOITE AND CYST TRANSCRIPTOME
To investigate the magnitude of the transcriptional changes occurring during the life cycle of Giardia lamblia we compared the transcriptome of trophozoites and cysts. Cysts were found to possess a much smaller transcriptome, both in terms of mRNA diversity and abundance. Genes encoding proteins ...
ORGANISM(S): Giardia intestinalis 
2011-11-09 | E-GEOD-25460 | biostudies-arrayexpress
GenomicsDifferential gene expression during encystation in Giardia intestinalis
Differential gene expression during encystation in Giardia intestinalis
PRJNA594734 | ENA
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