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TranscriptomicsTranscriptomic profiling of human neuromesodermal-like cells and spinal cord progenitors derived in vitro from H9 ES cell line
Human ES (H9) cells were directed towards a neuromesodermal progenitor-like cell state and these cells were then subsequently differentiated towards a neural cell fate. Human ES cells (H9) were differentiated into neuromesodermal progenitor-like cells by culturing in Neurobasal/1x N2/1x B27 medium (...
ORGANISM(S): Homo sapiens 
2018-07-04 | E-MTAB-6680 | biostudies-arrayexpress
GenomicsLandscape of protein SUMOylation on chromatin in hIPSCs (ChiPS4) by SUMO1 CHIP-seq
SUMO1 CHIP-seq experiment was performed in untreated hiPSC line - ChiPS4, to determine the exact locations of chromatin bound SUMO1 in these cells, thus providing information about the landscape of SUMOylation of protein targets on chromatin in human pluripotent cells and as such allowing for invest...
ORGANISM(S): Homo sapiens 
2022-12-01 | E-MTAB-9960 | biostudies-arrayexpress
TranscriptomicsTranscriptome changes in Slc7a5-null mouse embryos
The effects of loss of the large neutral amino acid transporter Slc7a5 (aka Lat1) on mouse embryonic development were investigated. Slc7a5 fl/fl mice harbouring two copies of the Slc7a5 targeted allele (exon 1 of Slc7a5 flanked with two loxP sites), were crossed with a mouse line ubiquitously expres...
ORGANISM(S): Mus musculus 
2019-06-01 | E-MTAB-6336 | biostudies-arrayexpress
TranscriptomicsRNA-seq of inflammatory monocytes, patrolling monocytes and neutrophils in wild type and ABIN1[D485N] mice
We have previously generated ABIN1[D485N] knock-in mice that appear relatively normal for 2 months after birth, but develop large spleen at 3 months, which is followed by the appearance of high levels of antibodies against self DNA and self-nuclear antigens and severe inflammation of the kidney and ...
ORGANISM(S): Mus musculus 
2019-11-04 | E-MTAB-8185 | biostudies-arrayexpress
OtherQuantitative proteome analysis of temporally resolved phagosomes following uptake via key phagocytic receptors
Data from ProteomeXchange, PXD ID: PXD000772. File: BMM_30-30_Phosphatidylserine-3.mzml. Published as part of Mol Cell Proteomics. 2015 May;14(5):1334-49 . From the Abstract: {{i}} ... In this study, we accurately quantified a proteomic time-course of isolated phagosomes from murine bone marrow-der...
ORGANISM(S): Mus_musculus_viruses, Mouse 
GPM11210041625 | GPMDB
Resource Reanalysis 
ProteomicsGlobal ubiquitylation analysis of mitochondria in primary neurons following PINK1-dependent activation of Parkin
Dataset analyzed in "Global ubiquitylation analysis of mitochondria in primary neurons following PINK1-dependent activation of Parkin" paper. Experiment TMT-labeled neurons untreated vs 5h AO treatment: 1) Membrane Proteome: .raw files AO2445-AO2456 2) Ubiquitylome: .raw files AO2433-AO2438 Experi...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2021-06-16 | MSV000087639 | MassIVE
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