Sort   by:  
 Page size 
TranscriptomicsIdentification of ploidy-regulated genes in budding yeast
Using RNA-seq, we analyzed the transcriptomes of isogenic haploid (MATa) and tetraploid (MATaaaa) budding yeast strains in the Sigma 1278b background and identified genes whose regulation was altered by ploidy. Analysis of poly(A)+ RNA from 2 biological replicates of haploid (MATa) and tetraploid (M...
ORGANISM(S): Saccharomyces cerevisiae 
2010-11-04 | E-GEOD-19685 | biostudies-arrayexpress
GenomicsLigand-dependent dynamics of retinoic acid receptor binding during early neurogenesis
Among its many roles in development, retinoic acid determines the anterior-posterior identity of differentiating motor neurons by activating Retinoic Acid Receptor (RAR)-mediated transcription. RAR is thought to bind the genome constitutively, and only induce transcription in the presence of the ret...
ORGANISM(S): Mus musculus 
2010-12-10 | E-GEOD-19409 | biostudies-arrayexpress
GenomicsInduced Cdx2 binding in embryonic stem cells and endodermal cells
Regulatory proteins can bind to different sets of genomic targets in various cell types or conditions. To reliably characterize such condition-specific regulatory binding we introduce MultiGPS, an integrated machine learning approach for the analysis of multiple related ChIP-seq experiments. MultiGP...
ORGANISM(S): Mus musculus 
2014-03-27 | E-GEOD-39435 | biostudies-arrayexpress
UnknownPatient-Reported Toxicity During Pelvic Intensity-Modulated Radiation Therapy: NRG Oncology-RTOG 1203.
Not available
S-EPMC6097832 | biostudies-literature
GenomicsDNase I hypersensitivity and algorithmic prediction of TF binding in early pancreatic mES directed differentiation
This dataset uses DNase-seq to profile the genome-wide DNase I hypersensitivity of mES and mES-derived cells along an early pancreatic lineage and provides the locations of putative Transcription Factor (TF) binding sites using the PIQ algorithm. DNase-seq takes advantage of the preferential cutting...
ORGANISM(S): Mus musculus 
2014-01-19 | E-GEOD-53776 | biostudies-arrayexpress
GenomicsHoxc9 ChIP-seq in differentiating motor neurons
The expression of v5-tagged Hoxc9 is induced and ChIP-seq is used to profile genome-wide occupancy in differentiating motor neurons The differentiation of ventral motor neurons is induced by treating embryonic stem cell cultures with retinoic acid and hedgehog signaling. Here, ChIP-seq is used to pr...
ORGANISM(S): Mus musculus 
2010-09-08 | E-GEOD-21812 | biostudies-arrayexpress
GenomicsEmbryonic stem cell based system for the discovery and mapping of developmental transcriptional programs
Chromatin immunoprecipitation followed by deep sequencing (ChIP-seq) is the method of choice to study function of transcription factors in cell fate determination. This technique faces two major obstacles when applied to developmental studies: the availability of ChIP grade antibodies and access to ...
ORGANISM(S): Mus musculus 
2011-11-12 | E-GEOD-30882 | biostudies-arrayexpress
Sort   by:  
 Page size