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GenomicsGigaxonin as a prognistic marker of human cancer
Gigaxonin as a prognistic marker of human cancer
PRJNA743670 | ENA
TranscriptomicsGigaxonin as a prognistic marker of human cancer
Gigaxonin, the GAN gene product, is a E3 ubiquitin ligase adaptor and is involved in neural cell and fibroblast intermediate filament processing. We have previously shown that gigaxonin in association with p16 ubiquitinates NF-κB in head and neck cancer. The cancer genomic database search has shown ...
ORGANISM(S): Homo sapiens 
2024-03-13 | GSE179424 | GEO
ProteomicsSILAC analysis of Gigaxonin Silenced Neurons
SILAC analysis of scramble and gigaxonin silenced dorsal root ganglia cultures
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-04-20 | MSV000091762 | MassIVE
UnknownGigaxonin is required for intermediate filament transport.
Not available
S-EPMC10237250 | biostudies-literature
UnknownGigaxonin Potentiates Antiviral Innate Immune Responses by Targeting cGAS and TREX1.
Not available
S-EPMC12667517 | biostudies-literature
UnknownGiant axonal neuropathy-associated gigaxonin mutations impair intermediate filament protein degradation.
Not available
S-EPMC3635735 | biostudies-literature
ProteomicsProteomic analysis in the gigaxonin null mouse model
Proteomic Analysis in the gigaxonin null mouse model. Analysis of whole brain and dorsal root ganglia tissue from 2M old mice.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-04-24 | MSV000091788 | MassIVE
UnknownGigaxonin E3 ligase governs ATG16L1 turnover to control autophagosome production.
Not available
S-EPMC6377711 | biostudies-literature
UnknownSonic Hedgehog repression underlies gigaxonin mutation-induced motor deficits in giant axonal neuropathy.
Not available
S-EPMC6877328 | biostudies-literature
UnknownThe Kelch 3 motif on gigaxonin mediates the interaction with NUDCD3 and regulates vimentin filament morphology.
Not available
S-EPMC12403043 | biostudies-literature
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