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TranscriptomicsRNASeq of MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946
Central to the molecular pathogenesis of MLL leukaemia is the abnormal co-optation of members of transcription complexes including disrupter of telomeric silencing 1-like (DOT1L) and bromodomain containing protein 4 (BRD4). Consequently, targeted therapies against DOT1L and BRD4 are currently being ...
ORGANISM(S): Homo sapiens 
2016-06-12 | E-GEOD-71777 | biostudies-arrayexpress
GenomicsChIPSeq of MV4;11 cell treated with DMSO, I-BET, SGC0946 and combination of I-BET and SGC0946
Central to the molecular pathogenesis of MLL leukaemia is the abnormal co-optation of members of transcription complexes including disrupter of telomeric silencing 1-like (DOT1L) and bromodomain containing protein 4 (BRD4). Consequently, targeted therapies against DOT1L and BRD4 are currently being ...
ORGANISM(S): Homo sapiens 
2016-06-12 | E-GEOD-71776 | biostudies-arrayexpress
GenomicsChIPSeq of MV4;11 cell treated with SGC0946 for 8 hours and washout
Central to the molecular pathogenesis of MLL leukaemia is the abnormal co-optation of members of transcription complexes including disrupter of telomeric silencing 1-like (DOT1L) and bromodomain containing protein 4 (BRD4). Consequently, targeted therapies against DOT1L and BRD4 are currently being ...
ORGANISM(S): Homo sapiens 
2016-06-12 | E-GEOD-71779 | biostudies-arrayexpress
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