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TranscriptomicsMicroarray expression profiling of MAIT subsets isolated from thymus of B6-MAIT/CAST mice, as compared to single positive CD4 or CD8 conventional T cells.
In mice, contrary to conventional T cells, MAIT cells acquire a memory phenotype in the thymus in relation with Zbtb16 expression (Savage et al., 2008 ; Koay et al., 2016). To define phenotypic transcriptional signatures of MAIT subsets in the thymus, we analyzed by microarray the transcriptome of M...
ORGANISM(S): Mus musculus 
2019-07-01 | E-MTAB-7702 | biostudies-arrayexpress
TranscriptomicsSingle cell RNA-seq of metabolite specific T-cells (MR1-restricted) from adult mouse thymus
Mucosal-Associated Invariant T cells (MAIT cells) have a unique specificity for the microbial metabolite 5-OP-RU presented by the non-classical presentation molecule MR1. Upon activation, they release cytotoxic mediators and engage an antimicrobial activity. As a subset of T lymphocytes, MAIT develo...
ORGANISM(S): Mus musculus 
2019-07-01 | E-MTAB-7704 | biostudies-arrayexpress
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