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TranscriptomicsEnvironmental Toxicants Induce Epigenetic Transgenerational Inheritance of Ovarian Disease
The epigenetic transgenerational actions of environmental toxicants and relevant mixtures on ovarian disease was investigated with the use of a fungicide, a pesticide mixture, a plastic mixture, dioxin and a hydrocarbon mixture. After transient exposure of an F0 gestating female rat during embryonic...
ORGANISM(S): Rattus norvegicus 
2012-03-01 | E-GEOD-33423 | biostudies-arrayexpress
TranscriptomicsStable pausing by RNA polymerase II provides an opportunity to target and integrate regulatory signals
Metazoan gene expression is often regulated after the recruitment of RNA polymerase II (Pol II) to promoters, through the controlled release of promoter-proximally paused Pol II into productive RNA synthesis. Despite the prevalence of paused Pol II, very little is known about the dynamics of these e...
ORGANISM(S): Drosophila melanogaster 
2013-10-31 | E-GEOD-49078 | biostudies-arrayexpress
GenomicsNational Human Genome Research Institute Tumor Sequencing Project (TSP) - Lung Adenocarcinoma

The Tumor Sequencing Project (TSP) Consortium is a collaboration among participants at the Baylor College of Medicine Human Genome Sequencing Center, the Broad Institute Genome Sequencing Platform, the Dana Farber Cancer Institute, the Memorial Sloan-Kettering Cancer Center, the Genome Seque...

phs000144.v1.p1 | EGA
TranscriptomicsHost genetic diversity enables experimental Ebola hemorrhagic fever pathogenesis
Zaire ebolavirus (ZEBOV) is among the deadliest known human pathogens, causing severe hemorrhagic fever with high case fatality rates ranging from 70-90%. The lack of effective vaccines or treatment available for ZEBOV renders this pathogen as a significant global biodefense threat, as evidenced by...
ORGANISM(S): Mus musculus 
2014-05-01 | E-GEOD-57214 | biostudies-arrayexpress
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