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HER2 targeting with trastuzumab has changed the prognosis of breast cancer patients carrying amplification and/or overexpression of this oncogene. Despite this progress, however, resistance to trastuzumab occurs in the vast majority of patients. Newer anti-HER2 therapies, like the dual tyrosine-kina...
ORGANISM(S): Homo sapiens 
Although the clinical differences between hemodialysis (HD) and peritoneal dialysis (PD) are well described, the specific biological mechanisms that cause these differences remain a subject of ongoing research. Omics-based approaches may help to elucidate these differences. To address this aim, we p...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD076533 | Pride
c-jun conditional knockout mice (c-jun?li) and relative controls (c-junf/f) were treated with TCPOBOP (3mg/Kg of body weight) and were sacrificed at 0, 1, 3 and 6 hours later. Gene expression analysis was performed on total RNA pools extracted from fresh frozen livers of 3 animals per group. For e...
ORGANISM(S): Mus musculus 
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