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ProteomicsCDK9-55 guides the anaphase-promoting complex/cyclosome (APC/C) in choosing the DNA repair pathway by affecting the UFL1 ubiquitination.
DNA double-strand breaks (DSBs) contribute to genome instability, a key feature of cancer. DSBs are mainly repaired by homologous recombination (HR) and non-homologous end-joining (NHEJ). We investigated the role of an isoform of the multifunctional cyclin-dependent kinase 9, CDK9-55, in DNA repair,...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-07-20 | MSV000087856 | MassIVE
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S-EPMC8801136 | biostudies-literature
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