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GenomicscKIT+ sorted cells from 57-137 day old fetal testes and ovaries
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2015-05-28 | E-GEOD-63394 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of cKIT+ sorted cells from 16-16.5 week old fetal testes and ovaries and RNA-Seq of TRA-1-60+ H1 hESCs
Generation of research quality, clinically relevant cell types in vitro from human pluripotent stem cells (hPSCs) requires detailed understanding of the equivalent cell types in humans. Here we analyzed 130 human fetal samples at 6-20 weeks of development and identified the stages in which human cKI...
ORGANISM(S): Homo sapiens 
2012-08-03 | E-GEOD-39821 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of cKIT+ sorted cells from 53-137 day old fetal testes and ovaries and RNA-Seq of TRA-1-81+ H1 and UCLA1 hESCs.
We performed RNA-Seq analyses on 15 human fetal samples at 53-137 days of development, 9 female and 5 male, and identified the transcriptional changes during the transition of human cKIT+ primordial germ cells (PGCs), the precursors of gametes, to the generation of Advanced Germline Cells. Comparing...
ORGANISM(S): Homo sapiens 
2015-05-28 | E-GEOD-63392 | biostudies-arrayexpress
GenomicsWhole Genome Bisulfite Sequencing (WGBS) of cKIT+ sorted cells from 57-137 day old fetal testes and ovaries.
We performed WGBS analyses on 6 human fetal samples at 53-137 days of development, 4 female and 2 male. We show that methylation reprogramming in the human germline is global yet incomplete with exons, 3’UTRs and human-specific transposons remaining methylated. Whole Genome Bisulfite-Seq of cKIT+ ce...
ORGANISM(S): Homo sapiens 
2015-05-28 | E-GEOD-63393 | biostudies-arrayexpress
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