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Effect of IBSP on patient-delived gliomasphere culture [microarray]
Some aspects of the gene expression-based classification method were robust because the gliomasphere cultures retained their classification over many passages, and IDH1 mutant gliomaspheres were all proneural. While gene expression of a subset of gliomasphere cultures was more like the parent tumor ...
ORGANISM(S): Homo sapiens 
2017-05-27 | GSE98995 | GEO
We aim to examine gene expression changes on patient-derived gliomasphere by IBSP treatment
ORGANISM(S): Homo sapiens 
2022-11-16 | GSE186931 | GEO
Dendritic cell (DC)-based immunotherapy against glioblastoma multiforme is a novel treatment hope. Glioblastoma stem-like cells are, however, potentially causing immunoresistance. Glioblastoma cells cultured as gliomaspheres show a stem-like phenotype as opposed to classical adherent culture. They a...
ORGANISM(S): Homo sapiens (Human) 
2019-04-15 | PXD008244 | Pride
Large-scale assessment of the gliomasphere model system
We report transcriptomes from 430 single glioblastoma cells isolated from 5 individual tumors and 102 single cells from gliomasphere cells lines generated using SMART-seq. In addition, we report population RNA-seq from the five tumors as well as RNA-seq from cell lines derived from 3 tumors (MGH26, ...
ORGANISM(S): Homo sapiens 
Transcriptomic characterization of GBM tumor and vascular cells and IBSP on patient-delived gliomasphere culture
Single-cell RNA-seq of primary GBM tumours and matched patient-derived organoids and gliomasphere lines. Obtained using the 10X Genomics single-cell 3' expression solution (v2 chemistry). Primary samples and PDOs from 12 tumours from 10 patients (10 primary, two recurrent), and gliomasphere lines fr...
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