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Systems biology is the study of complex living organisms, and as such, analysis on a systems-wide scale involves the collection of information-dense data sets that are representative of an entire phenotype. To uncover dynamic biological mechanisms, bioinformatics tools have become essential to fa...

2017-11-23 | MTBLS572 | MetaboLights

A multiplatform comparison of serum of smokers (n=56) and non-smokers (n=57) using NMR spectroscopy and UPLC-MS was carried out to determine perturbed biochemical functions associated with tobacco smoking. This should be helpful for establishing causal relationships between exposure and adverse e...

2017-01-09 | MTBLS364 | MetaboLights

The viral shunt is a fundamental ecosystem process which diverts the flux of organic carbon fixed through photosynthesis during algal bloom events from heterotrophic grazers to bacteria. Through the extracellular release of metabolites, lytic viral infections supply 2-10% of photosynthetically fi...

2025-10-08 | MTBLS11597 | MetaboLights
Mammalian genomes have evolutionary harbored numerous mobile elements, a part of which are still active and evoke genomic instability. Their movement and positional diversity occasionally result in phenotypic changes and variation by causing altered expression and disruption of neighboring genes in...
ORGANISM(S): Mus musculus 
Histone acetyltransferases (HATs) and deacetylases (HDACs) function antagonistically to control histone acetylation. As acetylation is a histone mark for active transcription, HATs have been associated with active and HDACs with inactive genes. We describe here genome-wide mapping of HATs and HDACs ...
ORGANISM(S): Homo sapiens 
Global mapping of PfCDP occupany on the genome of P. falciparum
Thiele2013 - Human metabolism global reconstruction (Recon 2) Community-driven global reconstruction of human metabolism (version 2.02). This model is described in the article: A community-driven global reconstruction of human me...
2005-01-01 | MODEL1109130000 | BioModels
Post-transcriptional regulation in eukaryotes requires cis- and trans-acting features and factors including RNA secondary structure, and RNA-binding proteins (RBPs). However, a comprehensive view of the structural and RBP interaction landscape of RNAs in the nucleus has yet to be compiled for any or...
ORGANISM(S): Arabidopsis thaliana 
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