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MetabolomicsSNAP25 inhibits glioma progression by regulating synapse plasticity via GLS-mediated glutaminolysis

INTRODUCTION: Neuronal activity regulated by synaptic communication exerts an important role in tumorigenesis and progression in brain tumors. Genes for soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) annotated with the function ‘vesicle’ about syn...

2021-08-12 | MTBLS2806 | MetaboLights
MetabolomicsGLS2KO vs WT mouse hepatocytes
Not available
ORGANISM(S): Mus musculus 
ST001952 | MetabolomicsWorkbench
GenomicsBradyrhizobium sp. Gls-1
Bradyrhizobium sp. Gls-1 Genome sequencing
PRJNA1160007 | ENA
GenomicsTranscriptomics profile of adipose and adipocyte with Gls perturbation
Transcriptomics profile of adipose and adipocyte with Gls perturbation
PRJNA1112901 | ENA
TranscriptomicsTranscriptomics profile of adipose and adipocyte with Gls perturbation
We generated single nucleus transcriptomic atlas for white and brown adipose tissue from adipocyte-specific Gls knockout mouse, and also generated bulk RNA-seq from in vitro differentiated human white adipocytes with/without GLS knock down.
ORGANISM(S): Homo sapiens Mus musculus 
2024-05-18 | GSE267800 | GEO
GenomicsComparative transcriptomic analysis of CD83+ly75+GCB cells in wild type and Gls B knockout models
Comparative transcriptomic analysis of CD83+ly75+GCB cells in wild type and Gls B knockout models
PRJNA1205557 | ENA
TranscriptomicsComparative transcriptomic analysis of CD83+ly75+GCB cells in wild type and Gls B knockout models
This study aims to characterize the transcriptome in wild type and Gls B KO CD83+ly75+GCB cells, and find the potential mechanism of the Gls B KO CD83+ly75+GCB cells。
ORGANISM(S): Mus musculus 
2026-01-12 | GSE285673 | GEO
GenomicsGlutaminase (GLS) was a target gene downstream of lithocholic acid inhibiting gallbladder cancer
Glutaminase (GLS) was a target gene downstream of lithocholic acid inhibiting gallbladder cancer
PRJNA792090 | ENA
ProteomicsRaf1 Regulates Glutamine Catabolism Crosslinking Mass Spectrometry
We discovered Raf1 binds directly to GLS to facilitate glutaminase activity in cancer cells in cells that are dependent on Raf1 for growth.
ORGANISM(S): Homo sapiens (Human) 
2026-08-20 | PXD082525 | Pride
Human Lc-ms/ms 
TranscriptomicsMicroarrays of Maize Recombinant Inbred Lines inoculated with Cercospora zeina, which causes grey leaf spot (GLS) disease
Global transcriptome profiling of leaf tissue from 100 RILs. All plants were field-grown and infected with GLS. Objective was to carry out systems genetics of the transcriptional responses to GLS, by overlaying results obtained from co-expression correlation analysis, eQTL analysis and QTL analysis.
ORGANISM(S): Zea mays 
2016-11-04 | GSE76242 | GEO
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