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Unknown
(569)
Genomics
(76)
Transcriptomics
(74)
Proteomics
(24)
Other
(2)
Metabolomics
(1)
Organisms
Mus musculus
(42)
Rattus norvegicus
(21)
Homo sapiens
(18)
Andropogon gerardi
(16)
Bacteria
(16)
Borrelia
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Botrytis cinerea
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Canis lupus familiaris
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Clostridium perfringens
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Cnidaria
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Cricetulus griseus
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Eukaryota
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Hepatitis B virus
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Human betaherpesvirus 5
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Japanese encephalitis virus group
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Miscanthus x giganteus
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Mycobacterium tuberculosis
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Orthoflavivirus
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Panicum virgatum
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Platyhelminthes
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Pseudomonas aeruginosa AES-1R
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Rickettsia
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Saccharomyces cerevisiae
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Schizosaccharomyces pombe
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Severe acute respiratory syndrome coronavirus 2
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Ovis aries
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Organisms
Mus musculus
(24)
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(12)
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(1)
Repository
ENA
(70)
geo
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biostudies-arrayexpress
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pride
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MassIVE
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iProX
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MetaboLights
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Tissue
Brain
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Cell culture
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Hippocampus
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Neocortex
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Telencephalon
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Disease
Fragile X syndrome
(2)
Alzheimer's disease
(1)
Amyotrophic lateral sclerosis
(1)
Huntington Disease
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Parkinson's disease
(1)
Technology Type
Mass Spectrometry
(16)
Shotgun proteomics
(8)
Affinity purification coupled with mass spectrometry proteomics
(3)
Bottom-up proteomics
(2)
Data-dependent acquisition
(2)
Data-independent acquisition
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Mass spectrometry
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Gel-based experiment
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SWATH MS
(1)
Instrument Platform
Illumina HiSeq 2500
(3)
Illumina HiSeq 4000
(3)
Single-Cell Extraction: For enzymatic digestion, pronase (Septomyces argeus, 1 mg/mL) was applied for 25 minutes at room temperature for P0 to P8 datasets. Cells were dissociated and triturated into a single-cell suspension in ACSF supplemented with 1% fetal calf serum (FCS) and DNase (1 µL/10 mL). Trituration was performed using three glass Pasteur pipettes of decreasing diameters. For P30 datasets, enzymatic digestion and cell dissociation were carried out using the Worthington Papain Dissociation System, following the manufacturer’s instructions. Single-Nuclei Extraction: For nuclei isolation, the Hibernate™-E Medium was removed, and 500 µL of chilled 0.1X NP40 Lysis Buffer was added. Tissue was homogenized using a Pellet Pestle (15 strokes) and incubated on ice for 5 minutes. The suspension was pipette-mixed 10 times using a wide-bore pipette tip and incubated for an additional 10 minutes on ice. Following lysis, 500 µL of chilled wash buffer was added, and the mixture was pipette-mixed 5 times using a regular-bore pipette tip. The suspension was filtered through a 30 µm cell strainer into a 50 mL tube to remove debris. The filtered suspension was transferred to a 1.5 mL tube and centrifuged at 950 × g for 10 minutes at 4°C. The supernatant was carefully removed, and the nuclei pellet was retained for downstream analysis.
(2)
Illumina NovaSeq 6000
(2)
Orbitrap Eclipse
(2)
Orbitrap Fusion Lumos
(2)
Chromium Next GEM Chip G
(1)
10X v3
(1)
NextSeq 500
(1)
QTRAP 6500
(1)
TripleTOF 6600
(1)
Liquid Chromatography MS - negative - reverse phase
(1)
Liquid Chromatography MS - positive - reverse phase
(1)
Publication Date
2025
(13)
2024
(13)
2026
(11)
2021
(11)
2020
(10)
2016
(10)
2019
(6)
2014
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2013
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2023
(4)
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(3)
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(3)
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2011
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2010
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2007
(1)
2006
(1)
2017
(1)
CHEBI ID
CHEBI:191894
(1)
CHEBI:89416
(1)
CHEBI:89059
(1)
CHEBI:35021
(1)
CHEBI:169166
(1)
CHEBI:36492
(1)
CHEBI:34131
(1)
CHEBI:34128
(1)
CHEBI:52386
(1)
CHEBI:46958
(1)
CHEBI:33993
(1)
CHEBI:88917
(1)
CHEBI:177252
(1)
CHEBI:170583
(1)
CHEBI:77694
(1)
CHEBI:177283
(1)
CHEBI:89513
(1)
CHEBI:89512
(1)
CHEBI:88918
(1)
CHEBI:177261
(1)
CHEBI:171349
(1)
CHEBI:81469
(1)
CHEBI:88990
(1)
CHEBI:170661
(1)
CHEBI:88414
(1)
CHEBI:77127
(1)
CHEBI:34160
(1)
CHEBI:25311
(1)
CHEBI:27978
(1)
CHEBI:80567
(1)
Metabolite Name
()-Pelletierine
(1)
(1S,4S)-Dihydrocarvone
(1)
1-Penten-3-ol
(1)
(S)-2-Methylbutanal
(1)
3-Methyl-3-buten-1-ol
(1)
2-Nonenal
(1)
8-Isoprostaglandin F2a
(1)
Maleylacetoacetic acid
(1)
3-Oxoglutaric acid
(1)
5alpha-Pregnan-20alpha-ol-3-one
(1)
Gamma-Glutamyltryptophan
(1)
5'-(3',4'-Dihydroxyphenyl)-gamma-valerolactone sulfate
(1)
Pentanal
(1)
Gamma-Aminobutyryl-lysine
(1)
Asparaginyl-Isoleucine
(1)
2-Arachidonylglycerol
(1)
Caffeic acid 3-sulfate
(1)
Luteolinidin
(1)
Adrenoyl ethanolamide
(1)
11,14,17-Eicosatrienoic acid
(1)
3,4-Dihydroxyphenylacetaldehyde
(1)
Norepinephrine sulfate
(1)
Estrone sulfate
(1)
2-Tetradecanone
(1)
Phenethylamine glucuronide
(1)
2-Maleylacetate
(1)
27-Deoxy-5b-cyprinol
(1)
LysoPC(22:5(7Z,10Z,13Z,16Z,19Z))
(1)
Putreanine
(1)
Prenol
(1)
First Public Date
2024
(12)
2025
(11)
2026
(10)
2021
(8)
2020
(7)
2019
(6)
2016
(4)
2014
(4)
2022
(3)
2023
(2)
2018
(2)
2017
(1)
Study type
Transcription profiling by array
(19)
RNA-seq of coding RNA
(3)
Animal - High-throughput sequencing
(2)
RNA-seq of coding RNA from single cells
(2)
Transcription profiling by SAGE
(1)
CLIP-seq
(1)
ChIP-seq
(1)
Release Date
2021
(61)
2022
(60)
2023
(59)
2024
(54)
2025
(48)
2020
(45)
2016
(36)
2019
(35)
2017
(34)
2014
(27)
2018
(27)
2015
(18)
2013
(12)
2007
(12)
2011
(10)
2010
(9)
2012
(8)
2009
(8)
2008
(8)
2006
(7)
2026
(6)
2005
(4)
2004
(4)
2003
(4)
2002
(1)
1997
(1)
Lab affiliation
1. CERVO Brain Research Centre, Quebec Mental Health Institute; Québec, QC, G1E 1T2, Canada. 2. Department of Psychiatry & Neuroscience, Université Laval; Québec, QC, G1V 0A6, Canada.
(1)
Centre for Discovery Brain Sciences, University of Edinburgh, UK; Simons Initiative for the Developing Brain, University of Edinburgh, UK
(1)
Departamento de Fisiologia, Laboratório de Fisiologia da Nutrição, Universidde Federal de São Paulo, Brasil
(1)
Department of Basic and Clinical Neuroscience, The Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology, & Neuroscience, King’s College London, London, UK
(1)
Department of Molecular Sciences, Faculty of Science and Engineering, Macquarie University, Sydney, NSW, Australia
(1)
Dept of Neurology University Hospital RWTH Aachen Pauwelsstrasse 30 52074 Aachen Germany
(1)
Division of Systems and Cellular Medicine School of Medicine University of Dundee
(1)
Faculty of Health Sciences, Department of Proteomics, The Novo Nordisk Foundation Centre for Protein Research, University of Copenhagen, DK-2200 Copenhagen, Denmark
(1)
Institut du Fer a Moulin, Inserm-Sorbonne Université UMR-S 1270, Paris, France
(1)
Institute of Physiology II University of Freiburg, Germany
(1)
Institute of Physiology II, Universität Freiburg, Germany
(1)
Kiraly Lab Dept of Psychiatry Friedman Brain Institue Icahn School of Medicine at Mount Sinai
(1)
Professor, Ophtalmology, School of Medicine, University of California, Sam Fancisco (UCSF)
(1)
Shenzhen eye hospital
(1)
University of Basel, Biozentrum, Switzerland
(1)
University of Warsaw, Warsaw, Poland
(1)
Tags
xref:PubMed:38632412
(4)
xref:PubMed:33127842
(3)
xref:PubMed:30136682
(2)
xref:PubMed:29636502
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xref:PubMed:41905693
(2)
xref:PubMed:34610266
(1)
xref:PubMed:30558641
(1)
xref:PubMed:34455026
(1)
xref:PubMed:36932057
(1)
xref:PubMed:40050441
(1)
xref:PubMed:29973860
(1)
xref:PubMed:40471331
(1)
xref:PubMed:36283406
(1)
xref:PubMed:38368460
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xref:PubMed:42433021
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xref:PubMed:24896097
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xref:PubMed:32479993
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xref:PubMed:40819006
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xref:PubMed:42160410
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xref:PubMed:40178780
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xref:PubMed:38968112
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xref:PubMed:42437753
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xref:PubMed:24302897
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xref:PubMed:40925985
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xref:PubMed:38187533
(1)
xref:PubMed:35063073
(1)
xref:PubMed:39946537
(1)
xref:PubMed:23763471
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xref:PubMed:39950545
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xref:PubMed:37239038
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Genetic Deletion of GABA
A
Receptors Reveals Distinct Requirements of Neurotransmitter Receptors for GABAergic and Glutamatergic Synapse Development.
Not available
S-EPMC6558517
|
biostudies-literature
Cite
The neuregulin-1 receptor erbB4 controls glutamatergic synapse maturation and plasticity.
Not available
S-EPMC2031848
|
biostudies-literature
Cite
Tiam1 is Critical for Glutamatergic Synapse Structure and Function in the Hippocampus.
Not available
S-EPMC6867819
|
biostudies-literature
Cite
An RNAi-based approach identifies molecules required for glutamatergic and GABAergic synapse development.
Not available
S-EPMC1950560
|
biostudies-literature
Cite
Gjd2b-mediated gap junctions promote glutamatergic synapse formation and dendritic elaboration in Purkinje neurons.
Not available
S-EPMC8382294
|
biostudies-literature
Cite
Apical-Basal Polarity Signaling Components, Lgl1 and aPKCs, Control Glutamatergic Synapse Number and Function.
Not available
S-EPMC6817635
|
biostudies-literature
Cite
Mutant LRRK2 enhances glutamatergic synapse activity and evokes excitotoxic dendrite degeneration.
Not available
S-EPMC4144018
|
biostudies-literature
Cite
D-Serine and Serine Racemase Are Associated with PSD-95 and Glutamatergic Synapse Stability.
Not available
S-EPMC4766304
|
biostudies-literature
Cite
To determine the differentially expressed genes in cancer associated fibroblasts upon ablation of the glutamatergic synapse protein NetrinG1. [RNA-Seq]
To determine the differentially expressed genes in cancer associated fibroblasts upon ablation of the glutamatergic synapse protein NetrinG1. [RNA-Seq]
PRJNA659668
|
ENA
Cite
MeCP2 controls excitatory synaptic strength by regulating glutamatergic synapse number.
Not available
S-EPMC2198899
|
biostudies-literature
Cite
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