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TranscriptomicsMechanistic evaluation and transcriptional signature of a Glutathione S-transferase Omega 1 inhibitor
Glutathione S-transferase omega 1 (GSTO1) is an atypical GST isoform that is overexpressed in several cancers and has been implicated in drug resistance. Currently, no small-molecule drug targeting GSTO1 is under clinical development. In this study we show that silencing of GSTO1 with siRNA signific...
ORGANISM(S): Homo sapiens 
2016-10-07 | GSE85899 | GEO
GenomicsDeletion of Glutathione S-Transferase Omega 1 Activates Type I Interferon Genes and Downregulates Tissue Factor
Deletion of Glutathione S-Transferase Omega 1 Activates Type I Interferon Genes and Downregulates Tissue Factor
PRJNA615849 | ENA
UnknownGlutathione transferase omega 1 catalyzes the reduction of S-(phenacyl)glutathiones to acetophenones.
Not available
S-EPMC2562259 | biostudies-literature
UnknownInhibition of glutathione S-transferase omega 1-catalyzed protein deglutathionylation suppresses adipocyte differentiation.
Not available
S-EPMC10471458 | biostudies-literature
UnknownMechanistic evaluation and transcriptional signature of a glutathione S-transferase omega 1 inhibitor.
Not available
S-EPMC5059489 | biostudies-literature
TranscriptomicsDeletion of Glutathione S-Transferase Omega 1 Activates Type I Interferon Genes and Downregulates Tissue Factor
Glutathione S-transferase omega 1 (GSTO1) is an atypical GST isoform that is overexpressed in several cancers and has been implicated in drug resistance. Currently, no small-molecule drug targeting GSTO1 is under clinical development. Using genetic tools, including extensive bioinformatics analysis ...
ORGANISM(S): Homo sapiens 
2020-09-16 | GSE147626 | GEO
UnknownGlutathione S-Transferase Omega 1 variation does not influence age at onset of Huntington's disease.
Not available
S-EPMC394327 | biostudies-literature
UnknownGlutathione s-transferase omega 1 activity is sufficient to suppress neurodegeneration in a Drosophila model of Parkinson disease.
Not available
S-EPMC3307323 | biostudies-literature
UnknownStructure-Based Design of N-(5-Phenylthiazol-2-yl)acrylamides as Novel and Potent Glutathione S-Transferase Omega 1 Inhibitors.
Not available
S-EPMC8855368 | biostudies-literature
UnknownRegioselective covalent immobilization of catalytically active glutathione S-transferase on glass slides.
Not available
S-EPMC3644561 | biostudies-literature
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