Glycoprotein m6a

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Unknown (23)
Transcriptomics (22)
Genomics (3)
Other (1)
Metabolomics (1)
Proteomics (1)

Organisms

Homo sapiens (14)
Mus musculus (8)
Saccharomyces cerevisiae SK1 (1)
Drosophila melanogaster (1)
Candidatus Methylomirabilis lanthanidiphila (1)
Brachyspira pilosicoli P43/6/78 (1)
Saccharomyces kudriavzevii ZP591 (1)
Metazoa (1)
Cryptococcus neoformans Tu401-MP_1 (1)
Kluyveromyces marxianus DMKU3-1042 (1)
Erythrobacter sp. RAS19 (1)
Epinephelus fuscoguttatus x Epinephelus lanceolatus (1)
Acinetobacter baumannii A424 (1)
Nesocodon mauritianus (1)
Felinae (1)
Hyaenidae (1)
Ursidae (1)
Bacillus phage phi3T-SPBeta hybrid (1)
Candida albicans 23R (1)
Pseudomonas chlororaphis (1)
Actinobacillus pleuropneumoniae serovar 2 (1)
Jaltomata herrerae (1)
uncultivated soil bacterium (1)
Plasmodium falciparum UGK 730.2 (1)
Orthoreovirus (1)
Mesoplasma florum L1 (1)
Octopus variabilis (1)
Bordetella bronchiseptica (1)
Vicia faba var. faba (1)
Giardia duodenalis assemblage B (1)

Organisms

Homo sapiens (1)
Mus musculus (1)

Repository

biostudies-arrayexpress (22)
geo (2)
ENA (2)
MetaboLights (1)
pride (1)

Tissue

Brain (1)

Disease

Erythroleukemia (1)
Adenocarcinoma (1)

Technology Type

Mass spectrometry (1)
Mass Spectrometry (1)
Shotgun proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (3)
-- (1)
Illumina NovaSeq X (1)
NextSeq 2000 (1)
NextSeq 550 (1)
Illumina HiSeq 4000 (1)
NextSeq 500 (1)
Liquid Chromatography MS - negative - HILIC (1)
Liquid Chromatography MS - positive - HILIC (1)

Publication Date

2025 (4)
2009 (4)
2026 (3)
2013 (3)
2021 (2)
2014 (2)
2010 (2)
2023 (1)
2022 (1)
2017 (1)
2015 (1)
2012 (1)
2020 (1)

Metabolite Name

(2,6-dihydroxy-4-{4-hydroxy-7-methyl-11-oxo-2,8-dioxatricyclo[7.3.1.0?,??]trideca-1(12),3,5(13),6,9-pentaen-3-yl}phenoxy)dihydroxyoxo-lambda?-sulfanylium (1)
(6-carboxy-3,4,5-trihydroxyoxan-2-yl)[3,5-dihydroxy-2-(3,4,5-trihydroxyphenyl)-7H-chromen-7-ylidene]oxidanium (1)
5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6-bis[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-4H-chromen-4-one (1)
Thymidine 3'-monophosphate (1)
6-(4-ethyl-2-methoxyphenoxy)-3,4,5-trihydroxyoxane-2-carboxylic acid (1)
6-{4-[6-(3,4-dihydroxyphenyl)-8,13-dihydroxy-4-oxo-3,11-dioxatricyclo[8.4.0.0?,?]tetradeca-1(10),2(7),8-trien-12-yl]-2-hydroxyphenoxy}-3,4,5-trihydroxyoxane-2-carboxylic acid (1)
Thr Ala (1)
NIPECOTIC ACID (1)
4-[2-(Propylamino)ethyl]-1,3-dihydro-2H-indol-2-one (1)
Gln Gln Tyr Phe (1)
1alpha,21-dihydroxy-20-oxo-22,23,24,25,26,27-hexanorvitamin D3 (1)
Gly Glu Ser Trp (1)
GPCho(17:1/17:1) (1)
Trp Met Tyr Val (1)
PGF2alpha Alcohol methyl ether (1)
PE(19:1(9Z)/18:4(6Z,9Z,12Z,15Z)) (1)
Gln Gln Phe Tyr (1)
Val Val Ser Lys (1)
3,4,5-trihydroxy-6-(2-{[2-(9-{[(2E)-2-methylbut-2-enoyl]oxy}-2-oxo-2H,8H,9H-furo[2,3-h]chromen-8-yl)propan-2-yl]oxy}-2-oxoethoxy)oxane-2-carboxylic acid (1)
Edetate (1)
(2-hydroxy-2-{9-hydroxy-7-oxo-2H,3H,7H-furo[3,2-g]chromen-2-yl}propoxy)sulfonic acid (1)
{[3,4-dihydroxy-4-(1-oxo-1H-isochromen-3-yl)butan-2-yl]oxy}sulfonic acid (1)
3,6,7-Trihydroxy-4'-methoxyflavone 7-rhamnoside (1)
PC(16:1(9Z)/22:6(4Z,7Z,10Z,13Z,16Z,19Z))[U] (1)
PC(16:0/20:5(5E,8E,11E,14E,17E))[U] (1)
GPCho(16:0/22:6) (1)
Alanyl-Asparagine (1)
15-cyclohexyl pentanor PGF2alpha (1)
Alpha-Campholene acetate (1)
[2-hydroxy-3-(7-hydroxy-4-oxo-4H-chromen-2-yl)-6-methoxyphenyl]oxidanesulfonic acid (1)

First Public Date

2025 (1)
2021 (1)

Study type

Transcription profiling by array (12)
RNA-seq of coding RNA (4)
Other (2)
Ribo-seq (1)
ChIP-seq (1)
RNA-seq of coding RNA from single cells (1)
RNA-seq of total RNA (1)

Release Date

2022 (5)
2023 (4)
2017 (4)
2013 (4)
2009 (4)
2026 (3)
2025 (3)
2021 (3)
2015 (2)
2014 (2)
2012 (2)
2010 (2)
2024 (1)
2020 (1)
2019 (1)
2018 (1)
2016 (1)
2011 (1)
2005 (1)

Lab affiliation

Group Leader. Laboratorio de Neurobiologia Molecular y Celular. Institutto de Investigaciones Biotecnologicas (IIBio) Consejo de Investigaciones Cientificas y Tecnicas (CONICET) Universidad Nacional de San Martin (UNSAM) (1)

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TMT spectrometry unveils key M6a interactorsTMT spectrometry unveils key M6a interactors

The membrane glycoprotein M6a -together with proteolipid protein (PLP), DM20 and M6b- belongs to the tetraspan PLP family. M6a is a neuronal surface protein that promotes neuronal stem cell differentiation, migration, neurite and axonal outgrowth, filopodia/spine induction and synapse formation in p...

ORGANISM(S): Rattus norvegicus (Rat)

2020-06-29 | PXD017347 | Pride

Yeast m6A methylated mRNAs are enriched on translating ribosomes during meiosis, and under Rapamycin treatment

Interest in mRNA methylation has exploded in recent years. The sudden interest in a 40 year old discovery was due in part to the recent finding of FTO?s (Fat Mass Obesity) N6-methyl-adenosine (m6A) deaminase activity, thus suggested a link between obesity-associated diseases and the presence of m6A...

ORGANISM(S): Saccharomyces cerevisiae SK1

2015-08-12 | E-GEOD-68435 | biostudies-arrayexpress

Identification and Characterization of the Mammalian Nuclear RNA N6-Adenosine Methyltransferase Core Complex

N6-methyladenosine (m6A) is the most prevalent internal modification found in mammalian messenger and non-coding RNAs. The discoveries of functionally significant demethylases that reverse this methylation as well as the recently revealed m6A distributions in mammalian transcriptomes strongly indica...

ORGANISM(S): Homo sapiens

2013-11-29 | E-GEOD-46705 | biostudies-arrayexpress

Neural glycoprotein M6a is released in extracellular vesicles and modulated by chronic stressors in blood.

Not available

S-EPMC5575271 | biostudies-literature

m6A-dependent regulation of messenger RNA stability

N6-methyladenosine (m6A) is the most prevalent internal modification present in the mRNA of all higher eukaryotes. Here we present that m6A is selectively recognized by human YTH domain family (YTHDF2) protein to regulate mRNA degradation. By using crosslinking and immunoprecipitation, we have ident...

ORGANISM(S): Homo sapiens

2013-11-29 | E-GEOD-49339 | biostudies-arrayexpress

Neuronal Glycoprotein M6a: An Emerging Molecule in Chemical Synapse Formation and Dysfunction.

Not available

S-EPMC8129562 | biostudies-literature

The Membrane Glycoprotein M6a Endocytic/Recycling Pathway Involves Clathrin-Mediated Endocytosis and Affects Neuronal Synapses.

Not available

S-EPMC5611492 | biostudies-literature

Identification of Potential Interacting Proteins With the Extracellular Loops of the Neuronal Glycoprotein M6a by TMT/MS.

Not available

S-EPMC7396582 | biostudies-literature

The Glycoprotein M6a Is Associated with Invasiveness and Radioresistance of Glioblastoma Stem Cells.