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For 13 patients with JAK2 exon 12-mutated polycythemia vera (PV), we compared genome-wide RNA profiles of JAK2-mutant (mutant) and wild-type erythroid colonies, grown from a single patient in the same culture plate. This paired approach controls for factors including age, gender, treatment, germline...
ORGANISM(S): Homo sapiens 
Sub-Saharan Africa currently experiences an unprecedented wave of urbanization, which has important consequences for health and disease patterns. This study aimed to investigate and integrate the immune and metabolic consequences of rural or urban lifestyles and the role of nutritional changes assoc...
2021-06-22 | MTBLS2267 | MetaboLights
Redox Responsive Transcription Factor1 (RRTF1) in Arabidopsis is rapidly and transiently upregulated by H202, as well as biotic and abiotic induced redox signals. Inactivation of RRTF1 restricts and overexpression promotes reactive oxygen species (ROS) accumulation in response to stress. Overexpress...
ORGANISM(S): Arabidopsis thaliana 
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