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no omics definedTranscription profiling of human patients with advances metastatic colo-rectal cancer - phase II exploratory pharmacogenomics study of cetuximab monotherapy
Patients with metastatic colorectal cancer were enrolled for treatment with cetuximab monotherapy. Transcriptional profiling was conducted on RNA from pre-treatment metastatic site biopsies to identify genes whose expression correlates with best clinical responses. Experiment Overall Design: single...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-5851 | biostudies-arrayexpress
TranscriptomicsRepertoire of miRNAs in epithelial ovarian cancer determined by next generation sequencing of small RNA cDNA libraries
Background: MicroRNAs (miRNAs) are small regulatory RNAs that are implicated in cancer pathogenesis and have recently shown promise as blood-based biomarkers for cancer detection. Epithelial ovarian cancer is a deadly disease for which improved outcomes could be achieved by successful early detectio...
ORGANISM(S): Homo sapiens 
2009-03-12 | E-GEOD-15190 | biostudies-arrayexpress
UnknownInherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer.
Not available
S-EPMC4302212 | biostudies-literature
ProteomicsLineage specific extracellular vesicle-associated protein biomarkers for the early detection of high grade serous ovarian cancer
High grade serous ovarian carcinoma (HGSOC) accounts for ~70% of ovarian cancer cases. Non-invasive, highly specific blood-based tests for pre-symptomatic screening in women are crucial to reducing the mortality associated with this disease. Since most HGSOCs typically arise from the fallopian tubes...
ORGANISM(S): Homo sapiens (Human) 
2023-10-09 | PXD036726 | Pride
Exosomes High grade serous Extracellular vesicles Ovarian cancer Fallopian tube Early detection Biomarkers 
TranscriptomicsFOXA1 actively represses the molecular phenotype of basal breast cancers.
Breast cancer is a heterogeneous disease comprised of at least five major subtypes. Luminal subtype tumors confer a more favourable patient prognosis, which is in part, attributed to the Estrogen Receptor-alpha (ER) positivity and anti-hormone responsiveness of these tumors. Expression of the forkhe...
ORGANISM(S): Homo sapiens 
2012-03-09 | E-GEOD-31003 | biostudies-arrayexpress
UnknownTargeting of mutant p53-induced FoxM1 with thiostrepton induces cytotoxicity and enhances carboplatin sensitivity in cancer cells.
Not available
S-EPMC4294351 | biostudies-literature
UnknownThe BCSC-1 locus at chromosome 11q23-q24 is a candidate tumor suppressor gene.
Not available
S-EPMC208790 | biostudies-literature
UnknownRobust gene expression and mutation analyses of RNA-sequencing of formalin-fixed diagnostic tumor samples.
Not available
S-EPMC4511951 | biostudies-literature
UnknownAn Integrated Approach to Protein Discovery and Detection From Complex Biofluids.
Not available
S-EPMC10388710 | biostudies-literature
UnknownThe Challenge of Home Allergen Re-introductions Using the Ladder Approach in Children With Non-IgE Mediated Gastrointestinal Food Allergy.
Not available
S-EPMC8974734 | biostudies-literature
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