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TranscriptomicsGene Expression Analysis of Transgenic Myc-Driven Liver Tumor Formation and Regression
Gene expression changes were examined in transgenic MYC-driven liver cancers at different time points as tumors formed and upon early regression. Time points evaluated include: Control (non-tumor bearing), Pre-tumor (mice were removed from doxyclycine in their diet to induce MYC oncogene expression...
ORGANISM(S): Mus musculus 
2011-07-06 | E-GEOD-28198 | biostudies-arrayexpress
UnknownPhase I dose-escalation study of 5-day intermittent oral lapatinib therapy in patients with human epidermal growth factor receptor 2-overexpressing breast cancer.
Not available
S-EPMC4017711 | biostudies-literature
TranscriptomicsmiRNA expression changes in murine liver tumorigenesis
Hepatocellular carcinoma (HCC) is associated with poor survival for patients and few effective treatment options, raising the need for novel therapeutic strategies. MicroRNAs (miRNAs) play important roles in tumor development and show deregulated patterns of expression in HCC. Because of the liver’s...
ORGANISM(S): Mus musculus 
2013-09-01 | E-GEOD-44570 | biostudies-arrayexpress
ProteomicsOncogene Regulated Release of Extracellular Vesicles
Oncogenes can alter metabolism by changing the balance between anabolic and catabolic processes. However, how oncogenes regulate tumor cell biomass remains poorly understood. Using isogenic MCF10A cells transformed with nine different oncogenes, we show that specific oncogenes reduce the biomass ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-04-16 | MSV000087219 | MassIVE
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