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UnknownPINK1 phosphorylates ubiquitin predominantly in astrocytes.
Not available
S-EPMC6906478 | biostudies-literature
ProteomicsQuantitative comparative analysis of human erythrocyte surface proteins between individuals from two genetically distinct populations
Red blood cells (RBC) play a critical role in oxygen transport, and are the focus of important human diseases including malaria and the haemoglobinopathies. Although previous studies aimed at classifying the RBC proteome have examined whole or membrane-enriched fractions from RBC, none have used spe...
ORGANISM(S): Homo sapiens (Human) 
2019-08-22 | PXD013852 | Pride
Erythrocyte Red blood cell Blood cell Cell surface Quantitative proteomics Tandem mass tag Plasma membrane 
UnknownThe Anemia Stress Index-Anemia, Transfusions, and Mortality in Patients with Continuous Flow Ventricular Assist Devices.
Not available
S-EPMC9369576 | biostudies-literature
UnknownA pathogenic variant in RAB32 causes autosomal dominant Parkinson's disease and activates LRRK2 kinase.
Not available
S-EPMC10827257 | biostudies-literature
ProteomicsYoun_et_al_RNAbodies_SAINT3105_Set1
This set of submissions contains the mass spectrometry files for the manuscript by Ji-Young Youn et al. that describes the high-density proximity mapping of RNA bodies. BioID experiments were performed from Flp-In T-REx HEK293 cells and MS files were acquired on Orbitrap Elite and Orbitrap Velos.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-08-04 | MSV000081411 | MassIVE
TranscriptomicspCREB-dependent transcriptional activation is a mediator of molecular neuroadaptations induced by methamphetamine self-administration in the rat dorsal striatum
Neuroplastic changes in the dorsal striatum participate in the transition from casual drug use to habitual and compulsive drug taking. These alterations might also play a critical role in the development of methamphetamine (METH) addiction. Nevertheless, the molecular substrates that underlie habitu...
ORGANISM(S): Rattus norvegicus 
2012-05-31 | E-GEOD-38223 | biostudies-arrayexpress
ProteomicsYoun_et_al_RNAbodies_SAINT3090_MSPLIT_DDA (PAIRED with MSV000081414)
This set of submissions contains the mass spectrometry files acquired using Data-Dependent Acquisition mode (DDA), which were paired with Data-Independent Acquisition mode (DIA) files (MSV000081414) for the manuscript by Ji-Young Youn et al. that describes the high-density proximity mapping of RNA b...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-01-17 | MSV000081947 | MassIVE
UnknownAlterations of PINK1-PRKN signaling in mice during normal aging.
Not available
S-EPMC11855339 | biostudies-literature
UnknownActivation of endogenous PRKN by structural derepression is linked to increased turnover of the E3 ubiquitin ligase.
Not available
S-EPMC12758189 | biostudies-literature
MetabolomicsDietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism

Ferroptosis is mediated by lipid peroxidation of phospholipids containing polyunsaturated fatty acyl moieties. Glutathione, the key cellular antioxidant capable of inhibiting lipid peroxidation via the activity of the enzyme glutathione peroxidase 4 (GPX-4), is generated directly from the sulfur-...

2023-01-11 | MTBLS5959 | MetaboLights
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