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Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge, CB2 0XY, UK (1)
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Seer Inc. (1)
Seer, Inc., Redwood City, CA 94065, USA (1)
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pathogen:bacterium (1)
pathogen (1)

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Genome-wide distribution of RNA-DNA hybrids identifies RNase H targets in tRNA genes, retrotransposons and mitochondria

During transcription the nascent RNA can invade the DNA template, forming extended RNA-DNA duplexes (R-loops). Here we employ ChIP-seq in strains expressing or lacking RNase H to map targets of RNase H activity throughout budding yeast genome. In wild-type strains, R-loops were readily detected over...

ORGANISM(S): Saccharomyces cerevisiae

2014-11-03 | E-GEOD-53420 | biostudies-arrayexpress

Validation of the Revised Olweus Bully/Victim Questionnaire (OBVQ-R) Among Adolescents in Chile.

Not available

S-EPMC8072054 | biostudies-literature

The SMAD-binding domain of SKI: a hotspot for de novo mutations causing Shprintzen-Goldberg syndrome.

Not available

S-EPMC4297897 | biostudies-literature

BRCA1 binds TERRA RNA and suppresses R-Loop-based telomeric DNA damage.

Not available

S-EPMC8192922 | biostudies-literature

A Rare Case of Shprintzen-Goldberg craniosynostosis syndrome with Hirschsprung disorder: Dental characteristics and its Clinical Management.

Not available

S-EPMC10767731 | biostudies-literature

Identification of regulators of polyploidization presents therapeutic targetsfor treatment of AMKL

Wen Q, Goldenson B, Silver SJ, Schenone M, Dancik V, Huang Z, Wang LZ, Lewis TA, An WF, Li X, Bray MA, Thiollier C, Diebold L, Gilles L, Vokes MS, Moore CB, Bliss-Moreau M, Verplank L, Tolliday NJ, Mishra R, Vemula S, Shi J, Wei L, Kapur R, Lopez CK, Gerby B, Ballerini P, Pflumio F, Gilliland DG, Go...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2014-01-27 | MSV000078536 | MassIVE

In-frame mutations in exon 1 of SKI cause dominant Shprintzen-Goldberg syndrome.

Not available

S-EPMC3487125 | biostudies-literature

The Goldberg-Huxley model of the pathway to psychiatric care: 21st-century systematic review.

Not available

S-EPMC10304946 | biostudies-literature

Effect size quantification for interrupted time series analysis: implementation in R and analysis for Covid-19 research.

Not available

S-EPMC9652048 | biostudies-literature

Origins of high catalyst loading in copper(i)-catalysed Ullmann-Goldberg C-N coupling reactions.