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TranscriptomicsTransmitted/founder hepatitis C viruses induce cell type- and genotype-specific differences in innate signaling within the liver
Primary human hepatocytes (PHHs) are a liver-specific cell subtype, and we have shown that these cells respond in a unique manner to the introduction of hepatitis C viral RNA (HCV vRNA) derived from different genotypes of the virus. We used microarray to analyze the transcriptional differences betwe...
ORGANISM(S): Homo sapiens 
2014-12-20 | E-GEOD-64400 | biostudies-arrayexpress
TranscriptomicsTranscriptional imprinting of transmigrating neutrophils on T84 intestinal epithelial cells
Neutrophil accumulation in crypt abscesses is a pathological hallmark of ulcerative colitis. Based on recent evidence that mucosal metabolic changes influence disease outcomes, we hypothesized that transmigrating neutrophils influence the transcriptional profile of intestinal epithelia. Microarray...
ORGANISM(S): Homo sapiens 
2012-10-31 | E-GEOD-39681 | biostudies-arrayexpress
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