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UnknownNadir testosterone within first year of androgen-deprivation therapy (ADT) predicts for time to castration-resistant progression: a secondary analysis of the PR-7 trial of intermittent versus continuous ADT.
Not available
S-EPMC4372851 | biostudies-literature
UnknownPhase I/II Trial of Labetuzumab Govitecan (Anti-CEACAM5/SN-38 Antibody-Drug Conjugate) in Patients With Refractory or Relapsing Metastatic Colorectal Cancer.
Not available
S-EPMC8259133 | biostudies-literature
UnknownEfficacy and Safety of Anti-Trop-2 Antibody Drug Conjugate Sacituzumab Govitecan (IMMU-132) in Heavily Pretreated Patients With Metastatic Triple-Negative Breast Cancer.
Not available
S-EPMC5559902 | biostudies-literature
TranscriptomicsTranscriptomic alterations in Trypanosoma cruzi-infected cardiac myocytes
Trypanosoma cruzi infection is a major cause of cardiomyopathy. Gene profiling studies of hearts from infected mice have revealed prominent changes in gene expression within many functional pathways. This variety of transcriptomic changes in infected mice raises the question of whether gene express...
ORGANISM(S): Mus musculus 
2010-05-15 | E-GEOD-17330 | biostudies-arrayexpress
TranscriptomicsTherapy with bone marrow cells recovers gene expression alterations in hearts of mice with chronic chagasic cardiomyopathy
Chronic chagasic cardiomyopathy is one of the leading causes of heart failure in Latin American countries, being associated with intense inflammatory response and fibrosis. We have previously shown that bone marrow mononuclear cell (BMC) transplantation improves inflammation, fibrosis and ventricula...
ORGANISM(S): Mus musculus 
2010-09-17 | E-GEOD-24088 | biostudies-arrayexpress
ProteomicsTrypOx, a novel eukaryotic homologue of the redox-regulated chaperone Hsp33 in Trypanosoma brucei
In this study, we describe a novel eukaryotic homologue of Hsp33 in Trypanosoma brucei.Bioinformatics analysis of the Hsp33 family suggested that eukaryotic pathogens belonging to the kinetoplastids, such as Trypanosoma cruzi,Trypanosoma brucei spp, and leishmaniasis had persevered Hsp33 homologues...
ORGANISM(S): Trypanosoma brucei 
2020-07-28 | PXD018965 | Pride
Trypanosoma brucei Lc-ms/ms 
UnknownAccelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks.
Not available
S-EPMC2836653 | biostudies-literature
TranscriptomicsIn-Vivo Fusion of Human Cancer and Hamster Stromal Cells Permanently Transduces and Transcribes Human DNA
The heterotransplantation of human tumors to immune-deprived rodents has become an important preclinical tool for evaluating human tumor biology and responsiveness to therapeutic agents, based on the supposition that they reflect their original human origin. However, we demonstrate that such tumors ...
ORGANISM(S): Homo sapiens 
2016-07-29 | E-GEOD-58277 | biostudies-arrayexpress
UnknownClinical, molecular, and genotype-phenotype correlation studies from 25 cases of oral-facial-digital syndrome type 1: a French and Belgian collaborative study.
Not available
S-EPMC2564504 | biostudies-literature
GenomicCCHMC - eMERGE Data

This submission includes genotyping data from 6 separate cohorts (named A-E here), each is described in separate paragraphs below.

Cohort A) Autism is a neurodevelopmental disorder that affects 1.5 million people in the United States, at an estimated lifetime cost of $4 million. It ...

phs000494 | dbGaP
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